Fast and effective prediction of microRNA/target duplexes.
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Summary
A program is presented, RNA-hybrid, that predicts multiple potential binding sites of miRNAs in large target RNAs and applied this method to the prediction of Drosophila miRNA targets in 3'UTRs and coding sequence.
- Type
- article
- Published
- 2004-10-01
- Cited by
- 2,517
- References
- 38
- Access
- Open access
- OpenAlex
- https://openalex.org/W2094253263
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:25962714
Keywords
Biology, microRNA, RNA, Computational biology, Base pair
References
- Prediction of plant microRNA targets.
- The Caenorhabditis elegans hunchback-like gene lin-57/hbl-1 controls developmental time and is regulated by microRNAs.
- A discipline of dynamic programming over sequence data
- Short-range cell interactions and cell survival in the Drosophila wing.
- Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure.
- The C elegans hunchback homolog, hbl-1, controls temporal patterning and is a probable microRNA target.
- Optimal computer folding of large RNA sequences using thermodynamics and auxiliary information
- Rapid and accurate estimates of statistical significance for sequence data base searches.
- Where is the ?c?
- bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila.
- Identification of Drosophila MicroRNA Targets
- Computational identification of microRNA targets
- Self-assembly of mesoscopically ordered chromatic polydiacetylene/silica nanocomposites
- Micro RNAs are complementary to 3′ UTR sequence motifs that mediate negative post-transcriptional regulation
- Methods for assessing the statistical significance of molecular sequence features by using general scoring schemes.
- UTRdb and UTRsite: specialized databases of sequences and functional elements of 5' and 3' untranslated regions of eukaryotic mRNAs
- Vienna RNA secondary structure server
- Design, implementation and evaluation of a practical pseudoknot folding algorithm based on thermodynamics
- Developmental functions of the Distal-less/Dlx homeobox genes.
- Specificity of microRNA target selection in translational repression.
Cited by
- Gene expression regulators —MicroRNAs
- miRNAMap: genomic maps of microRNA genes and their target genes in mammalian genomes
- Prediction of microRNA targets.
- RNAplex: a fast tool for RNA-RNA interaction search
- Overexpressed miR-494 down-regulates PTEN gene expression in cells transformed by anti-benzo(a)pyrene-trans-7,8-dihydrodiol-9,10-epoxide.
- MAGIA, a web-based tool for miRNA and Genes Integrated Analysis
- MicroRNAs 15a/16-1 function as tumor suppressor genes in multiple myeloma.
- Stars and Symbiosis: MicroRNA- and MicroRNA*-Mediated Transcript Cleavage Involved in Arbuscular Mycorrhizal Symbiosis1[W][OA]
- miR‐198 inhibits migration and invasion of hepatocellular carcinoma cells by targeting the HGF/c‐MET pathway
- MicroRNA-32 upregulation by 1,25-dihydroxyvitamin D3 in human myeloid leukemia cells leads to Bim targeting and inhibition of AraC-induced apoptosis
- Dynamic Modulation of Thymic MicroRNAs in Response to Stress
- MicroRNA-125b/Lin28 Pathway Contributes to the Mesendodermal Fate Decision of Embryonic Stem Cells
- In-silico and in-vivo analyses of EST databases unveil conserved miRNAs from Carthamus tinctorius and Cynara cardunculus
- Multiple microRNAs may regulate the DNA repair enzyme uracil-DNA glycosylase.
- Characterization and differential expression of microRNAs in the ovaries of pregnant and non-pregnant goats (Capra hircus)
- RNAplex a Fast and Flexible RNA-RNA Interaction Search Tool
- CLIP-based prediction of mammalian microRNA binding sites
- Prediction of miRNA targets.
- miR-638 Regulates Differentiation and Proliferation in Leukemic Cells by Targeting Cyclin-dependent Kinase 2*
- Knockdown of long non-coding RNA XIST exerts tumor-suppressive functions in human glioblastoma stem cells by up-regulating miR-152.
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