Platelet-derived growth factor expression and stimulation in human meningiomas.
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Summary
These studies support the hypothesis that PDGF acts as a growth factor in meningiomas and suggest that the beta receptor is functional: when it is activated, c-fos levels are increased, and an increase inMeningioma cell division is observed after the addition of PDGF-BB.
- Type
- article
- Published
- 1994-09-01
- Cited by
- 101
- References
- 18
- OpenAlex
- https://openalex.org/W2094249300
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:33156947
Keywords
Platelet-derived growth factor receptor, Platelet-derived growth factor, Growth factor, Receptor, Endocrinology
References
- Estrogen receptor immunoreactivity in meningiomas. Comparison with the binding activity of estrogen, progesterone, and androgen receptors.
- Immunocytochemical localization of progesterone receptors in breast cancer with anti-human receptor monoclonal antibodies.
- Treatment of unresectable meningiomas with the antiprogesterone agent mifepristone.
- Platelet-derived growth factor induces rapid but transient expression of the c-fos gene and protein
- Correlation of meningioma hormone receptor status with hormone sensitivity in a tumor stem-cell assay.
- Enhanced expression of the sis and c-myc oncogenes in human meningiomas.
- Growth factors in development, transformation, and tumorigenesis.
- Characterization of the epidermal growth factor receptor in human meningioma.
- Androgen receptor binding activity in meningiomas.
- B-type receptor for platelet-derived growth factor mediates a chemotactic response by means of ligand-induced activation of the receptor protein-tyrosine kinase.
- Human meningiomas co‐express platelet‐derived growth factor (pdgf) and pdgf‐receptor genes and their protein products
- Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease.
- Deletion of Alu sequences in the fifth c-sis intron in individuals with meningiomas.
- Endothelial cell hyperplasia in human glioblastoma: coexpression of mRNA for platelet-derived growth factor (PDGF) B chain and PDGF receptor suggests autocrine growth stimulation.
- Coexpression of platelet-derived growth factor (PDGF) and PDGF-receptor genes by primary human astrocytomas may contribute to their development and maintenance.
- Progesterone receptor expression in meningiomas.
- Hormonotherapy of meningiomas with medroxyprogesterone acetate. Immunohistochemical demonstration of the effect of medroxyprogesterone acetate on growth fractions of meningioma cells using the monoclonal antibody Ki-67.
Cited by
- Meningiomas: science and surgery.
- Molecular aspects of neuro-oncology.
- Molecular biological determinants of meningioma progression and aggressive behavior.
- The molecular biology of hormone and growth factor receptors in meningiomas.
- Phenotypic Change of Human Cultured Meningioma Cells
- Inhibition of PDGF receptor signaling in tumor stroma : effects on interstitial hypertension, drug uptake and therapeutic response.
- Detection of activated platelet-derived growth factor receptors in human meningioma.
- Recurrent anaplastic meningioma treated by sunitinib based on results from quantitative proteomics
- Involvement of platelet-derived growth factor in disease: development of specific antagonists.
- Platelet-derived growth factor in human brain tumors
- Hormonal dependency of cerebral meningiomas.
- Expression and activation of epidermal growth factor receptors in meningiomas.
- Receptor tyrosine kinases as rational targets for prostate cancer treatment: platelet-derived growth factor receptor and imatinib mesylate.
- Two distinct primary brain tumors, in same region of the same patient: a case report
- The biology of meningiomas
- Meningiomas: role of vascular endothelial growth factor/vascular permeability factor in angiogenesis and peritumoral edema.
- Correlation of vascular endothelial growth factor messenger RNA expression with peritumoral vasogenic cerebral edema in meningiomas.
- Phase II trial of sunitinib for recurrent and progressive atypical and anaplastic meningioma.
- Tenascin in Meningioma: Expression Is Correlated with Anaplasia, Vascular Endothelial Growth Factor Expression, and Peritumoral Edema But Not with Tumor Border Shape
- Extracellular matrix degradation by metalloproteinases and central nervous system diseases
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