Development of a prospective isopropyl alcohol-loaded pharmaceutical base using simultaneous in vitro/in vivo characterization methods of skin performance
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Summary
Evaluating APG-stabilized bases and their impact on skin performance recommend the investigated emulsifier for stabilization of topical drug delivery systems not only for their ability to sustain the addition of isopropyl alcohol which proved to be a valuable enhancer, but also satisfactory skin absorption and tolerability when compared to samples stabilized by conventional emulsifiers.
- Type
- article
- Published
- 2014-06-12
- Cited by
- 12
- References
- 48
- OpenAlex
- https://openalex.org/W2092821132
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:24607192
Keywords
In vivo, Isopropyl myristate, Isopropyl alcohol, Biopharmaceutical, Stratum corneum
References
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- Non-invasive in vivo methods for investigation of the skin barrier physical properties.
- Optimization of skin permeation and distribution of ibuprofen by using nanostructures (coagels) based on alkyl vitamin C derivatives.
- EEMCO guidance for the assessment of stratum corneum hydration: electrical methods
- The determination of stratum corneum thickness: an alternative approach.
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- The development and registration of topical pharmaceuticals.
- Phase and aggregation behaviour of alkylglycosides
Cited by
- Topical delivery of acetyl hexapeptide-8 from different emulsions: influence of emulsion composition and internal structure.
- Razvoj in vitro metode za ispitivanje oslobađanja djelatne tvari iz polimernih mikročestica za topičku primjenu
- Critical quality attributes, in vitro release and correlated in vitro skin permeation-in vivo tape stripping collective data for demonstrating therapeutic (non)equivalence of topical semisolids: A case study of "ready-to-use" vehicles.
- Heat-Integrated Azeotropic Distillation and Extractive Distillation for the Separation of Heterogeneous Ternary Azeotropes of Diisopropyl Ether/Isopropyl Alcohol/Water
- Bacillus licheniformis levan as a functional biopolymer in topical drug dosage forms: From basic colloidal considerations to actual pharmaceutical application.
- The evolution of process design and control for ternary azeotropic separation: Recent advances in distillation and future directions
- Formulation Design and Preclinical Evaluations of Surface Modified Lipid Nanoparticles-Coupled Gel Encapsulating Dihydroartemisinin for Treatment of Localized Inflammation
- Energy-Efficient Hybrid Reactive-Extractive Distillation with a Preconcentration Column for Recovering Isopropyl Alcohol and Diisopropyl Ether from Wastewater: Process Design, Optimization, and Intensification
- Solubility and thermodynamic study of mesalazine in propylene glycol + 2-propanol mixtures
- Alkyl Polyglucoside-based delivery systems: In vitro/in vivo skin absorption assessment
- Process Design and Optimization of the Reactive-Extractive Distillation Process Assisted with Reaction Heat Recovery Via Side Vapor Recompression for the Separation of Water-Containing Ternary Azeotrope
- Natural Emulsifiers of the Alkyl Polyglucoside Type and Their Influence on the Permeation of Drugs
- Towards Alkyl Polyglucoside-stabilized formulations: Influence of some common excipients
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