Immunohistochemical Staining for DNA Mismatch Repair Proteins in Intestinal Tract Carcinoma: How Reliable are Biopsy Samples?
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Summary
This study provides data indicating that biopsy samples are as reliable as resections in the immunohistochemical detection of mismatch repair protein abnormality in intestinal cancers.
- Type
- article
- Published
- 2011-03-01
- Cited by
- 86
- References
- 23
- OpenAlex
- https://openalex.org/W2087835419
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:11421494
Keywords
Lynch syndrome, MSH6, PMS2, MSH2, Pathology
References
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- Immunohistochemistry as First-line Screening for Detecting Colorectal Cancer Patients at Risk for Hereditary Nonpolyposis Colorectal Cancer Syndrome: A 2-antibody Panel May be as Predictive as a 4-antibody Panel
- Patterns of Morphologic Alteration in Residual Rectal Carcinoma Following Preoperative Chemoradiation and Their Association With Long-term Outcome
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- Immunohistochemistry for PMS2 and MSH6 alone can replace a four antibody panel for mismatch repair deficiency screening in colorectal adenocarcinoma
- Hereditary and Familial Colon Cancer
Cited by
- Lynch or not Lynch? Is that always a question?
- A practical guide to biomarkers for the evaluation of colorectal cancer
- The utility of diagnostic biopsy specimens for predictive molecular testing in colorectal cancer
- Immunohistochemistry staining for mismatch repair proteins: the endoscopic biopsy material provides useful and coherent results.
- Managing Young Colorectal Cancer: A UK and Irish Perspective
- Current Lynch Syndrome Tumor Screening Practices: A Survey of Genetic Counselors
- Endoscopic biopsies from gastrointestinal carcinomas and their suitability for molecular analysis: a review of the literature and recommendations for clinical practice and research
- How reliable is immunohistochemical staining for DNA mismatch repair proteins performed after neoadjuvant chemoradiation?
- Immunohistochemistry in Gastroenterohepatopancreatobiliary Epithelial Neoplasia: Practical Applications, Pitfalls, and Emerging Markers.
- Preoperative Diagnosis of Lynch Syndrome With DNA Mismatch Repair Immunohistochemistry on a Diagnostic Biopsy
- Lynch syndrome-associated neoplasms: a discussion on histopathology and immunohistochemistry
- Should Microsatellite Instability Be Tested in All Cases of Colorectal Cancer?
- [Colorectal Carcinoma with Suspected Lynch Syndrome: A Multidisciplinary Algorithm].
- Should the grading of colorectal adenocarcinoma include microsatellite instability status?
- The Utility of Immunohistochemistry for Providing Genetic Information on Tumors
- Lynch Syndrome Screening Should Be Considered for All Patients With Newly Diagnosed Endometrial Cancer
- Low Mutational Burden of Eight Genes Involved in the MAPK/ERK, PI3K/AKT, and GNAQ/11 Pathways in Female Genital Tract Primary Melanomas
- BRAF refines clinical interpretation of mismatch repair deficiency in colorectal cancer
- Heterogenous mismatch-repair status in colorectal cancer
- Reflex immunohistochemistry and microsatellite instability testing of colorectal tumors for Lynch syndrome among US cancer programs and follow-up of abnormal results.
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