Microsatellite instability in colorectal cancer
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Summary
MSI-H seems to be an important prognostic factor in CRC and an important predictive factor of CRC chemotherapeutic treatment efficacy, and is going to be the object of the future research.
- Type
- article
- Published
- 2011-03-15
- Cited by
- 1,405
- References
- 74
- Access
- Open access
- OpenAlex
- https://openalex.org/W1984307543
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:1952618
Keywords
Microsatellite instability, MLH1, MSH6, Colorectal cancer, MSH2
References
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- Cellular effects of CPT‐11 on colon carcinoma cells: Dependence on p53 and hMLH1 status
- Sensitivity to CPT-11 of xenografted human colorectal cancers as a function of microsatellite instability and p53 status
- Carcinogenesis. Missing mismatch repair.
- Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformation
- Concerted nonsyntenic allelic loss in human colorectal carcinoma.
- Does microsatellite instability predict the efficacy of adjuvant chemotherapy in colorectal cancer? A systematic review with meta-analysis.
- Microsatellite instability in cancer of the proximal colon.
- Genomic instability and colon cancer
- Prognostic significance of microsatellite instability in sporadic colorectal cancer
- Genetic Alterations During Colorectal-Tumor Development
- A genetic model for colorectal tumorigenesis.
- Microsatellite instability in human cancer: a prognostic marker for chemotherapy?
- High‐frequency microsatellite instability predicts better chemosensitivity to high‐dose 5‐fluorouracil plus leucovorin chemotherapy for stage IV sporadic colorectal cancer after palliative bowel resection
Cited by
- Identification of novel factors that promote trinucleotide repeat instability
- High Frequency Microsatellite Instability Has a Prognostic Value in Endometrial Endometrioid Adenocarcinoma, But Only in FIGO Stage 1 Cases
- Familial gastric cancer: update for practice management
- Checkpoint Signaling, Base Excision Repair, and PARP Promote Survival of Colon Cancer Cells Treated with 5-Fluorodeoxyuridine but Not 5-Fluorouracil
- The relationship between tumour site, clinicopathological characteristics and cancer‐specific survival in patients undergoing surgery for colorectal cancer
- Prognostic impact of β-2-microglobulin expression in colorectal cancers stratified by mismatch repair status
- Identification of a novel deletion mutant strain in Saccharomyces cerevisiae that results in a microsatellite instability phenotype
- Unusual Presentation of Recurrent Early Stage Endometrial Carcinoma 28 Years after Primary Surgery
- Signalling pathway impact analysis based on the strength of interaction between genes
- Impact of MLH1 expression on tumor evolution after curative surgical tumor resection in a murine orthotopic xenograft model for human MSI colon cancer
- Evaluating Mismatch Repair Deficiency in Pancreatic Adenocarcinoma: Challenges and Recommendations
- Prognostic Significance and Clinicopathological Features of Synchronous Colorectal Cancer
- Estudi de variants de significat desconegut en la síndrome de Lynch
- Potentialisation de la virothérapie anti-tumorale basée sur des adénovirus oncolytiques dans le traitement des cancers côliques et rénaux
- Genetic pathways, prevention, and treatment of sporadic colorectal cancer
- Epidemiology, molecular changes, histopathology and diagnosis of colorectal cancer
- New insights into the mechanism of DNA mismatch repair
- Isolation and characterisation of colon cancer stem cells and the effects of epigenetic modulation on pluripotent markers
- Overexpressed of RAD51 suppresses recombination defects: a possible mechanism to reverse genomic instability
- Étude des couples chimiokines/récepteurs comme nouvelles cibles thérapeutiques des cancers colorectaux métastasés : études précliniques
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