Binding of APC to the Human Homolog of the Drosophila Discs Large Tumor Suppressor Protein
Explore this paper's citation graph
Summary
Results suggest that the APC-DLG complex may participate in regulation of both cell cycle progression and neuronal function.
- Type
- article
- Published
- 1996-05-17
- Cited by
- 462
- References
- 35
- OpenAlex
- https://openalex.org/W2085252478
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:45284802
Keywords
Suppressor, Drosophila (subgenus), Biology, Drosophila melanogaster, Cell biology
References
- Somatic mutations of the APC gene in colorectal tumors: mutation cluster region in the APC gene.
- Clustering of Shaker-type K+ channels by interaction with a family of membrane-associated guanylate kinases
- The 220-kD protein colocalizing with cadherins in non-epithelial cells is identical to ZO-1, a tight junction-associated protein in epithelial cells: cDNA cloning and immunoelectron microscopy
- Subcellular localization of the APC protein: immunoelectron microscopic study of the association of the APC protein with catenin.
- Cellular interactions in development : a practical approach
- SAP90, a rat presynaptic protein related to the product of the Drosophila tumor suppressor gene dlg-A.
- Wild-type but not mutant APC associates with the microtubule cytoskeleton.
- APC binds to the novel protein EB1.
- The APC gene product associates with microtubules in vivo and promotes their assembly in vitro.
- Association of the APC tumor suppressor protein with catenins.
- Molecular identification of a major palmitoylated erythrocyte membrane protein containing the src homology 3 motif.
- Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients.
- Identification and characterization of the familial adenomatous polyposis coli gene
- High levels of expression of the tumor suppressor gene APC during development of the rat central nervous system
- The multistep nature of cancer.
- Localization of the gene for familial adenomatous polyposis on chromosome 5
- APC mutations occur early during colorectal tumorigenesis
- Association of plakoglobin with APC, a tumor suppressor gene product, and its regulation by tyrosine phosphorylation.
- Use of colloidal gold particles in double-labeling immunoelectron microscopy of ultrathin frozen tissue sections
- Identification of FAP locus genes from chromosome 5q21.
Cited by
- beta-Catenin is a target for extracellular signals controlling cadherin function: the neurocan-GalNAcPTase connection.
- Localization of proteins to the apico-lateral junctions of Drosophila epithelia.
- Potential interplay between luminal growth factors and increased tight junction permeability in epithelial carcinogenesis.
- Nuclear-cytoplasmic shuttling of APC regulates β-catenin subcellular localization and turnover
- Dlg, Scrib and Lgl regulate neuroblast cell size and mitotic spindle asymmetry
- Human homolog of Drosophila tumor suppressor Scribble negatively regulates cell‐cycle progression from G1 to S phase by localizing at the basolateral membrane in epithelial cells
- CDK phosphorylation of the discs large tumour suppressor controls its localisation and stability
- Analysis of Cell Polarity Signaling in C. elegans : A Dissertation
- Regulation of microtubule-associated proteins.
- The Role of PKCι in Cell Polarity, Mitosis and Cancer
- Characterisation of APC localisation, dynamics and functions at the centrosome
- Identification des partenaires neuronaux des protéines STOP
- The role of the PSD95/Dlg/ZO-1 (PDZ) binding motif of human papillomavirus type 18 E6 oncoprotein in the virus life cycle
- APC in cell migration.
- PDZ domains and the formation of protein networks at the plasma membrane.
- Càncer colorectal hereditari: Aplicacions diagnòstiques de l'estudi de la dosi dels gens APC, MLH1 i MSH2
- Hereditary desmoid disease due to a frameshift mutation at codon 1924 of the APC gene.
- Regulation of HTLV-I oncoprotein Tax by PDLIM2
- Janus Kinases and Focal Adhesion Kinases Play in the 4.1 Band: A Superfamily of Band 4.1 Domains Important for Cell Structure and Signal Transduction
- Chemoprevention of Cancer
Related papers
- Drosophilids with darker cuticle have higher body temperature under light
- Drosophilid cuticle pigmentation impacts body temperature
- Analysis of Drosophila melanogaster life span
- Methods to Assay the Behavior of Drosophila melanogaster for Toxicity Study.
- The Influence of Age and Sex of the Germ Cells on the Frequency of Mutation in Drosophila Simulans and Drosophila Melanogaster.
- The spontaneous mutation rate in Drosophila simulans.
- Drosophila melanogaster males respond differently at the behavioural and genome‐wide levels to Drosophila melanogaster and Drosophila simulans females