Preferential excision of the 5' proximal intron from mRNA precursors with two introns as mediated by the cap structure.
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Summary
The cap structure exerts its effect primarily on the 5' proximal intron, and differential splicing reactions of the two introns are not due to differences in the intrinsic efficiency of splicing of each intron.
- Type
- article
- Published
- 1987-08-01
- Cited by
- 104
- References
- 3
- Access
- Open access
- OpenAlex
- https://openalex.org/W2083872838
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:20853044
Keywords
Intron, RNA splicing, Exon, Group II intron, Precursor mRNA
References
Cited by
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- Regulatory Mechanisms and RNA Targets of Human Pumilio Proteins.
- Cell cycle-dependent regulation of the human RNA cap methyltransferase (RNMT)
- Investigating the cellular mechanisms that determine RNMT dependency in breast cancer cells
- Capping enzyme in eukaryotic mRNA synthesis.
- Mammalian in vitro splicing assays.
- A simple model to explain evolutionary trends of eukaryotic gene architecture and expression
- Structural Studies of a New Nuclear Target for EGF Receptor Tyrosine Kinase
- Biochemical characterisation of tRNA-Asp methyltransferase Dnmt2 and its physiological significance
- Isolation and characterization of the Candida albicans gene for mRNA 5′‐triphosphatase: association of mRNA 5′‐triphosphatase and mRNA 5′‐guanylyltransferase activities is essential for the function of mRNA 5′‐capping enzyme in vivo 1
- The Drosophila suppressor of sable protein binds to RNA and associates with a subset of polytene chromosome bands
- mRNAs that mature through trans-splicing in Caenorhabditis elegans have a trimethylguanosine cap at their 5' termini
- Lesions in the mRNA cap-binding gene ABA HYPERSENSITIVE 1 suppress FRIGIDA-mediated delayed flowering in Arabidopsis.
- The cap and the 3' splice site similarly affect polyadenylation efficiency
- On the path to genetic novelties: insights from programmed DNA elimination and RNA splicing
- A glucose-6-phosphate dehydrogenase (G6PD) splice site consensus sequence mutation associated with G6PD enzyme deficiency.
- RNA splicing capability of live neuronal dendrites.
- Signal Transduction and Post-Transcriptional Gene Expression
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