Selection for in vivo regulators of bacterial virulence
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Summary
It is shown that phenotypes that appear genetically independent in cell culture become interrelated in the host milieu and are identified as regulators of cholera toxin and a central virulence gene regulator that are operative during infection.
- Type
- article
- Published
- 2001-06-05
- Cited by
- 216
- References
- 24
- Access
- Open access
- OpenAlex
- https://openalex.org/W2083528938
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:205255568
Keywords
Virulence, Vibrio cholerae, Biology, Gene, Regulator
References
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- Initiation of biofilm formation in Pseudomonas fluorescens WCS365 proceeds via multiple, convergent signalling pathways: a genetic analysis
- Host‐induced, stage‐specific virulence gene activation in Candida albicans during infection
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- Control of bacterial chemotaxis
- DNA sequence of both chromosomes of the cholera pathogen Vibrio cholerae
- Regulatory cascade controls virulence in Vibrio cholerae.
- Use of recombinase gene fusions to identify Vibrio cholerae genes induced during infection
- Roles of motility and flagellar structure in pathogenicity of Vibrio cholerae: analysis of motility mutants in three animal models
- Regulation and temporal expression patterns of Vibrio cholerae virulence genes during infection.
- Alterations in Vibrio cholerae motility phenotypes correlate with changes in virulence factor expression
- Transient Transcriptional Activation of theVibrio cholerae El Tor Virulence Regulator ToxT in Response to Culture Conditions
Cited by
- Expression of flagella is coincident with uropathogenic Escherichia coli ascension to the upper urinary tract
- PhoB Regulates Motility, Biofilms, and Cyclic di-GMP in Vibrio cholerae
- Regulation of flagellar motility during biofilm formation
- Identification and characterization of virulence associated factors of C. jejuni
- Genetic tools to study gene expression during bacterial pathogen infection.
- Functional Characterization Of The Cholera Toxin Promoter Of vibrio Cholerae
- Vibrio cholerae interactions with the gastrointestinal tract: lessons from animal studies.
- mechanisms for bicarbonate-mediated virulence in Vibrio cholerae
- The mechanism for inhibition of Vibrio cholerae virulence gene expression by bile and its fatty acid components
- Intestinal Colonization Dynamics of Vibrio cholerae
- The role of CheV in S. typhimurium chemotaxis
- Quorum sensing and pathogenesis: role of small signalling molecules in bacterial persistence
- Prevailing concepts of c-di-GMP signaling.
- Studies on Ribotyping, Integron Genes and Pathogenicity of Marine Vibrios
- DSB proteins and bacterial pathogenicity
- Estudio de la funcionalidad de ToxR en cepas atenuadas de Vibrio cholerae O139
- Hypoxia‐induced localization of chemotaxis‐related signaling proteins in Vibrio cholerae
- A mouse model for direct evaluation of cholera vaccines
- Etudes Biochimique et Structurale de DsbA1, DsbA2 et DsbA3 : les trois homologues à l'oxydoréductase de Thiol-disulfure DsbA chez Neisseria meningitidis.
- Identification of an aerotaxis transducer in Vibrio cholerae
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