Endothelial expression of a mononuclear leukocyte adhesion molecule during atherogenesis.

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Summary

In dietary hypercholesterolemic and Watanabe heritable hyperlipidemic rabbit models of atherosclerosis, this inducible rabbit endothelial adhesion molecule was found to be expressed in a localized fashion by aortic endothelium that overlies early foam cell lesions, suggesting a potential endothelia-dependent mechanism for mononuclear leukocyte recruitment during atherogenesis.

Type
article
Published
1991-02-15
Cited by
1,797
References
31

Keywords

Cell adhesion molecule, Endothelium, Peripheral blood mononuclear cell, Soluble cell adhesion molecules, Adhesion

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