A total synthesis of dragmacidin B

Keywords

Chemistry, Total synthesis, Piperazine, Stereochemistry, Simple (philosophy)

References

• Dragmacidin, a new cytotoxic bis(indole) alkaloid from a deep water marine sponge, Dragmacidon spShigeo Kohmoto, Yoel Kashman, Oliver J. McConnell — 1988
• THE ELECTRIC MOMENTS OF SOME N,N′-DISUBSTITUTED PIPERAZINESM. V. George, George F Wright — 1958
• Metal-halogen exchange of bromoindoles. A route to substituted indolesMikel P. Moyer, John F. Shiurba, Henry Rapoport — 1986
• 6-BROMOTRYPTAMINE DERIVATIVES FROM THE GULF OF CALIFORNIA TUNICATE DIDEMNUM CANDIDUMEoin Fahy, Barbara C. M. Potts, D. John Faulkner — 1991
• Monosubstitution of Symmetrical Piperazine-2,5-dione DerivativesTW Badran, CJ Easton — 1990
• Brominated bis(indole) alkaloids from the marine sponge Hexadella sp.Sandra A. Morris, Raymond J. Andersen — 1990
• A new bis-(indole) alkaloid from a deep-water marine sponge of the genus SpongosoritesAmy E. Wright, Shirley A. Pomponi, Sue S. Cross — 1992
• Eudistomins A-Q, β-carbolines from the antiviral Caribbean tunicate Eudistoma olivaceumKenneth L. Rinehart, Jun’ichi Kobayashi, Gary C. Harbour — 1987

Cited by

• Muscarine, oxazole, thiazole, imidazole and peptide alkaloids and other miscellaneous alkaloids.Aída Terrón Bañuelos, Violeta Álvarez Fernández, Carmen Diego Pérez — 1992
• More than Forty Years of Organosulfur Chemistry and Many Other StudiesMichael P. Cava — 1998
• Total synthesis of marine bisindole alkaloids, (+)-hamacanthins A, B and (−)-antipode of cis-dihydrohamacanthin BTakashi Kouko, Ken Matsumura, Tomomi Kawasaki — 2005
• Marine indole alkaloids containing an 1-(indol-3-yl)ethane-1,2-diamine fragment (Review)Никита Е. Голанцов, Alexey А. Festa, Alexander V. Karchava — 2013
• Synthesis of the cycloheptannelated indole fragment of dragmacidin EBin Wang, Hua Qin, Fengying Zhang — 2014
• 1-Bromo-2,4-dihydro-1H-pyrazino[2,1-b]quinazoline-3,6-diones as α-bromoglycine templatesMarı́a Luisa Heredia, María Alejandra Mazo Fernández, Elena de la Cuesta — 2001
• 2,5-Diketopiperazines: synthesis, reactions, medicinal chemistry, and bioactive natural products.Alan D. Borthwick — 2012
• Asymmetric aminohydroxylation of vinyl indoles: a short enantioselective synthesis of the bisindole alkaloids dihydrohamacanthin A and dragmacidin ACai‐Guang Yang, Jun Wang, Xiaoxia Tang — 2002
• First total synthesis of dragmacidin A via indolylglycines.Tomomi Kawasaki, Hidetaka Enoki, Ken Matsumura — 2000
• Recent progress in the chemistry of non-monoterpenoid indole alkaloidsMasataka Ihara, Keiichiro Fukumoto — 2010
• Total Synthesis of (±)- and (−)-Actinophyllic AcidConnor L. Martin, Larry E. Overman, Jason M. Rohde — 2010
• An Improved, One-Pot Synthesis of 3,6-Bis(3'-indolyl)- 1 ,4-dimethylpiperazine-2,5-dioneDarryl R. Miles, Christine R. Whitlock — 2009
• C-H activation: a complementary tool in the total synthesis of complex natural products.David Y.‐K. Chen, So Won Youn — 2012
• 2-Halo-diketopiperazines as chiral glycine cation equivalentsSteven D. Bull, Stephen G. Davies, A. Christopher Garner — 2004
• Asymmetric organocatalytic synthesis of 4,6-bis(1H-indole-3-yl)-piperidine-2 carboxylates.Sabilla Zhong, Martin Nieger, Angela Bihlmeier — 2014
• Dragmacidin E synthesis studies. Preparation of a model cycloheptannelated indole fragment.Ken S. Feldman, Paiboon Ngernmeesri — 2005
• Total syntheses of chaetocin and ent-chaetocinEriko Iwasa, Yoshitaka Hamashima, Shinya Fujishiro — 2011
• A unified synthetic approach to the pyrazinone dragmacidins.Neil K. Garg, Brian M. Stoltz — 2006
• 3,6-Bis(5'-bromo-3'-indolyl)-1,4-dimethypiperazine-2,5-dioneStephen N. Crooke, Michele Davis-McGibony, Christine R. Whitlock — 2009
• Syntheses of bis(indolyl)-piperazine alkaloids, dragmacidin B and C, and dihydrohamacanthin ATomomi Kawasaki, Kohsuke Ohno, Hidetaka Enoki — 2002

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