2,5-Diketopiperazines: synthesis, reactions, medicinal chemistry, and bioactive natural products.
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- Type
- review
- Published
- 2012-05-11
- Cited by
- 728
- References
- 553
- OpenAlex
- https://openalex.org/W2022939277
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:12893829
Keywords
Citation, Icon, Altmetrics, Chemistry, Social media
References
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- A virosome-mimotope approach to synthetic vaccine design and optimization: synthesis, conformation, and immune recognition of a potential malaria-vaccine candidate.
- Exocellular Cyclic Dipeptides from a Ruegeria Strain Associated with Cell Cultures of Suberites domuncula
- Phosphoproteomic analysis of the effect of cyclo-[His-Pro] dipeptide on PC12 cells.
- NPI-2358 is a tubulin-depolymerizing agent: in-vitro evidence for activity as a tumor vascular-disrupting agent
- The Anticancer Agent Chaetocin Is a Competitive Substrate and Inhibitor of Thioredoxin Reductase
- Maremycin A and B, new diketopiperazines from a marine Streptomyces sp.
- Identification of Streptomyces sp. AMLK-335 producing antibiotic substance inhibitory to vancomycin-resistant enterococci
- Recent advances in the chemistry of cholecystokinin receptor ligands (agonists and antagonists).
- Synthesis and biological activities of phenylahistin derivatives.
- Peptides: The Wave of the Future
- Recent Advances in the Chemistry of 1-Hydroxyindoles, 1-Hydroxytryptophans, and 1-Hydroxytryptamines
- Activation of the amide group by acylation hydroxy- and aminoacyl incorporation in peptide systems.
- Novel low-molecular-weight inhibitor of PAI-1 (XR5118) promotes endogenous fibrinolysis and reduces postthrombolysis thrombus growth in rabbits.
- Fumitremorgin C reverses multidrug resistance in cells transfected with the breast cancer resistance protein.
- Genotoxicity assessment of five tremorgenic mycotoxins (fumitremorgen B, paxilline, penitrem A, verruculogen, and verrucosidin) produced by molds isolated from fermented meats.
- Apoptosis‐inducing effect of diketopiperazine disulfides produced by Aspergillus sp. KMD 901 isolated from marine sediment on HCT116 colon cancer cell lines
- Acetic acid-catalyzed diketopiperazine synthesis.
Cited by
- A one-pot multicomponent coupling/cyclization for natural product herbicide (±)-thaxtomin A.
- Algicidal activity of Bacillus sp. Lzh-5 and its algicidal compounds against Microcystis aeruginosa
- A Survey of the Role of Noncovalent Sulfur Interactions in Drug Design.
- Two novel cyclic hexapeptides from the genetically engineered Actinosynnema pretiosum
- Tubulin inhibitors targeting the colchicine binding site: a perspective of privileged structures.
- Synthesis of monoalkylidene diketopiperazines and application to the synthesis of barettin
- Reconstitution of Enzymatic Carbon-Sulfur Bond Formation Reveals Detoxification-Like Strategy in Fungal Toxin Biosynthesis.
- Switching a regular tryptophan C4-prenyltransferase to a reverse tryptophan-containing cyclic dipeptide C3-prenyltransferase by sequential site-directed mutagenesis.
- Synthesis, docking study and inhibitory activity of 2,6-diketopiperazines derived from α-amino acids on HDAC8.
- Efficient synthesis of 5-(hydroxymethyl)piperazin-2-ones using automatically prepared chiral bromocarboxylic acid and Garner's aldehyde as versatile building blocks.
- Aldol condensation with 2,5-diketopiperazines
- Inhibition of the MDM2/p53 Interaction Design, Synthesis and Evaluation of MDM2 Inhibitors
- Antibacterial activity of diketopiperazines isolated from a marine fungus using t-butoxycarbonyl group as a simple tool for purification.
- Asymmetric Synthesis of Tryptophan Driviatives and Its Application to Streamlined Synthesis of Tryprosatain A and B
- A new diketopiperazine derivative from a deep sea-derived Streptomyces sp. SCSIO 04496
- Rational and combinatorial tailoring of bioactive cyclic dipeptides
- Cyclo(d‐Tyr‐d‐Phe): a new antibacterial, anticancer, and antioxidant cyclic dipeptide from Bacillus sp. N strain associated with a rhabditid entomopathogenic nematode
- Total synthesis of (-)-depyranoversicolamide B.
- Design, synthesis and biological evaluation of soluble 2,5-diketopiperazines derivatives as potential antifouling agents
- Gelation capability of cysteine-modified cyclo(L-Lys-L-Lys)s dominated by Fmoc and Trt protecting groups
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