Antibiotic resistance and its cost: is it possible to reverse resistance?
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Summary
The findings suggest that the fitness costs of resistance will allow susceptible bacteria to outcompete resistant bacteria if the selective pressure from antibiotics is reduced, and that the rate of reversibility will be slow at the community level.
- Type
- review
- Published
- 2010-04-01
- Cited by
- 2,270
- References
- 140
- Access
- Open access
- OpenAlex
- https://openalex.org/W2073556554
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:40465398
Keywords
Antibiotic resistance, Biology, Antibiotics, Bacteria, Resistance (ecology)
References
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- Fitness costs associated with class IIa bacteriocin resistance in Listeria monocytogenes B73
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- Initial Drug Resistance and Tuberculosis Treatment Outcomes: Systematic Review and Meta-analysis
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- EPISTASIS BUFFERS THE FITNESS EFFECTS OF RIFAMPICIN‐ RESISTANCE MUTATIONS IN PSEUDOMONAS AERUGINOSA
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- VraR Binding to the Promoter Region of agr Inhibits Its Function in Vancomycin-Intermediate Staphylococcus aureus (VISA) and Heterogeneous VISA
- In vitro and in vivo fitness costs associated with Mycobacterium tuberculosis RpoB mutation H526D.
- Regulatory genes coordinating antibiotic‐induced changes in promoter activity and early transcriptional termination of the mycobacterial intrinsic resistance gene whiB7
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- Silver nanoparticles with pH induced surface charge switchable properties for antibacterial and antibiofilm applications.
- intI1 Type Mobile Genetic Elements Co-selected Antibiotic-Resistant Genes in Untreated Hospital Wastewaters
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