Mammalian Fe-S cluster biogenesis and its implication in disease.
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Summary
This review will give an overview on what is known on mammalian Fe-S cluster biogenesis today, by putting it into the context of what is know from studies from lower model organisms, and focuses on the associated diseases, by drawing attention to the respective mutations.
- Type
- review
- Published
- 2014-05-01
- Cited by
- 104
- References
- 146
- Access
- Open access
- OpenAlex
- https://openalex.org/W2073251235
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:13142420
Keywords
Biogenesis, Context (archaeology), Iron–sulfur cluster, Biology, Mitochondrion
References
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- The structure of aconitase
Cited by
- Mechanisms Underlying the Essential Role of Mitochondria in Chronological Aging of the Yeast Saccharomyces cerevisiae
- Functional reconstitution of mitochondrial Fe/S cluster synthesis on Isu1 reveals the involvement of ferredoxin
- Iron-Induced Damage in Cardiomyopathy: Oxidative-Dependent and Independent Mechanisms
- Iron regulatory protein 1 sustains mitochondrial iron loading and function in frataxin deficiency.
- Mechanisms by Which Different Functional States of Mitochondria Define Yeast Longevity
- The roles of glutaredoxins ligating Fe-S clusters: Sensing, transfer or repair functions?
- Structure-function analysis of NEET proteins uncovers their role as key regulators of iron and ROS homeostasis in health and disease.
- Fe-S Cluster Biogenesis in Isolated Mammalian Mitochondria
- Biogenesis of cytosolic and nuclear iron-sulfur proteins and their role in genome stability.
- Dysregulation of cellular iron metabolism in Friedreich ataxia: from primary iron-sulfur cluster deficit to mitochondrial iron accumulation
- The role of mitochondria in cytosolic-nuclear iron–sulfur protein biogenesis and in cellular iron regulation.
- Mitochondrial iron homeostasis and its dysfunctions in neurodegenerative disorders.
- [Iron and sulfur in proteins. How does the cell build Fe-S clusters, cofactors essential for life?].
- Compartmentalization of iron between mitochondria and the cytosol and its regulation.
- Evidences for the non-redundant function of A-type proteins ISCA1 and ISCA2 in iron-sulfur cluster biogenesis
- The conserved protein Dre2 uses essential [2Fe-2S] and [4Fe-4S] clusters for its function in cytosolic iron-sulfur protein assembly.
- Mitochondrial Bol1 and Bol3 function as assembly factors for specific iron-sulfur proteins
- Iron-sulfur clusters in mitochondrial metabolism: Multifaceted roles of a simple cofactor
- Mitochondria and Iron: Current Questions
- New Techniques for Ancient Proteins: Direct Coupling Analysis Applied on Proteins Involved in Iron Sulfur Cluster Biogenesis
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