The transactivation and DNA binding domains of the BPV-1 E2 protein have different roles in cooperative origin binding with the E1 protein.

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Summary

The studies indicate that the E2 transactivation domain is sufficient for interaction with the E1 protein and that theE2 DNA binding domain is required for interactionWith origin DNA sequences.

Type
article
Published
1996-07-01
Cited by
37
References
1
Access
Open access

Keywords

Transactivation, Biology, SeqA protein domain, Binding domain, HMG-box

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