Unwinding of a Herpes Simplex Virus Type 1 Origin of Replication (OriS) by a Complex of the Viral Origin Binding Protein and the Single-Stranded DNA Binding Protein

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Summary

A herpes simplex virus type 1 (HSV-1) OriS analogue in which the A+T sequence linking the box I and II elements was replaced by two single-stranded oligo(dT)s is unwound by the UL9 protein-ICP8 complex, which supports a model for the unwinding of OriS.

Type
article
Published
2000-06-15
Cited by
30
References
11
Access
Open access

Keywords

Single-stranded binding protein, Biology, Ter protein, DNA replication, DNA

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