Angiotensin II induces smooth muscle cell proliferation in the normal and injured rat arterial wall.
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Summary
The present study explored the possibility that neointimal smooth muscle cells, the characteristic cells of restenosis and atherosclerosis, are selectively stimulated to replicate by a hypertensive stimulus and significantly increased DNA synthesis in the media of the carotid artery.
- Type
- article
- Published
- 1991-02-01
- Cited by
- 807
- References
- 35
- Access
- Open access
- OpenAlex
- https://openalex.org/W2071782926
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:33625138
Keywords
Neointima, Restenosis, Angiotensin II, Internal medicine, Vascular smooth muscle
References
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- Localization of angiotensinogen messenger RNA in rat aorta.
- Vascular Smooth Muscle Cell Hypertrophy and Hyperploidy in the Goldblatt Hypertensive Rat
- Cytoskeletal Features of Rat Aortic Cells during Development: An Electron Microscopic, Immunohistochemical, and Biochemical Study
- Effect of a Monoclonal Antibody to Angiotensin II on Hemodynamic Responses to Noradrenergic Stimulation in Pithed Rats
Cited by
- Accumulation of fetal fibronectin mRNAs after balloon denudation of rabbit arteries.
- Angiotensin II type 1 receptor blockade inhibits the expression of immediate-early genes and fibronectin in rat injured artery.
- Pathobiology of intimal hyperplasia
- TGF-beta promotes proliferation of cultured SMC via both PDGF-AA-dependent and PDGF-AA-independent mechanisms.
- Congenital renal tubular dysplasia and skull ossification defects similar to teratogenic effects of angiotensin converting enzyme (ACE) inhibitors.
- Angiotensin II induces vascular smooth muscle cell replication independent of blood pressure.
- Early intracellular signalling pathway of ethanol in vascular smooth muscle cells
- Regulation of Akt by arachidonic acid and phosphoinositide 3-kinase in angiotensin II-stimulated vascular smooth muscle cells.
- Vascular smooth muscle insulin resistance, but not hypertrophic signaling, is independent of angiotensin II-induced IRS-1 phosphorylation by JNK.
- Chronic hydrogen-rich saline treatment reduces oxidative stress and attenuates left ventricular hypertrophy in spontaneous hypertensive rats
- Living high training low induces physiological cardiac hypertrophy accompanied by down-regulation and redistribution of the renin-angiotensin system
- Angiotensin-converting enzyme gene polymorphism and common carotid stiffness. The Rotterdam study.
- Vascular smooth-muscle-cell activation: proteomics point of view.
- Angiotensin II-stimulated vascular endothelial growth factor expression in bovine retinal pericytes.
- ROLE OF CYCLOOXYGENASE-2 IN ABDOMINAL AORTIC ANEURYSMS IN MICE
- Angiotensin II Receptors and Angiotensin II-Stimulated Signal Transduction
- ANG II potentiates mitogenic effect of norepinephrine in vascular muscle cells: role of FGF-2.
- The role of growth factors in vascular cell development and differentiation.
- Angiotensin-converting enzyme inhibitor versus angiotensin II, AT1 receptor antagonist. Effects on smooth muscle cell migration and proliferation after balloon catheter injury.
- Can Angiotensin-converting Enzyme Inhibitors Reverse Atherosclerosis?
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