Mitotic recombination in haematological malignancy.
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Summary
It appears that, in a proportion of AMLs, the recombination leads to outgrowth of one of the daughter cells because of a selective advantage due to loss of wild type and/or gain of mutant sequence.
- Type
- review
- Published
- 2010-01-01
- Cited by
- 5
- References
- 73
- OpenAlex
- https://openalex.org/W2071226401
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:27803536
Keywords
PRC2, Biology, Missense mutation, Histone H3, Uniparental disomy
References
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- Bloom's syndrome. XX. The first 100 cancers.
- Genetic clonal diversity predicts progression to esophageal adenocarcinoma
- Association between acquired uniparental disomy and homozygous gene mutation in acute myeloid leukemias.
- Cell-cycle progression rates and sister chromatid exchange frequencies in the bone marrow of patients with myelodysplastic syndrome and acute myeloid leukemia.
- Expression of recessive alleles by chromosomal mechanisms in retinoblastoma
- Loss of Imprinting of Igf2 Alters Intestinal Maturation and Tumorigenesis in Mice
- Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias.
- A manyfold increase in sister chromatid exchanges in Bloom's syndrome lymphocytes.
- Genetic Alterations During Colorectal-Tumor Development
- Identification of RUNX1/AML1 as a classical tumor suppressor gene
- The Wt1+/R394W Mouse Displays Glomerulosclerosis and Early-Onset Renal Failure Characteristic of Human Denys-Drash Syndrome
- Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia.
- Frequent CBL mutations associated with 11q acquired uniparental disomy in myeloproliferative neoplasms.
- Reversible tumorigenesis by MYC in hematopoietic lineages.
Cited by
- Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders
- Inactivation of polycomb repressive complex 2 components in myeloproliferative and myelodysplastic/myeloproliferative neoplasms.
- Patterns and frequencies of acquired and constitutional uniparental isodisomies in pediatric and adult B‐cell precursor acute lymphoblastic leukemia
- MDSにおけるacquired uniparental disomyとc-CBL変異
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