Pexophagy: The Selective Autophagy of Peroxisomes
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Summary
This work has found that upon glucose- or ethanol-induced catabolite inactivation of metabolically superfluous peroxisomes are rapidly and selectively degraded within the vacuole by a process called pexophagy, the selective removal of per oxisomes by autophagy-like processes.
- Type
- review
- Published
- 2005-04-13
- Cited by
- 283
- References
- 49
- Access
- Open access
- OpenAlex
- https://openalex.org/W2071214201
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:21533238
Keywords
Peroxisome, Yarrowia, Biology, Yeast, Biochemistry
References
- A Pichia pastoris VPS15 homologue is required in selective peroxisome autophagy
- Trs85 is required for macroautophagy, pexophagy and cytoplasm to vacuole targeting in Yarrowia lipolytica and Saccharomyces cerevisiae.
- Tagging Hansenula polymorpha genes by random integration of linear DNA fragments (RALF)
- A ubiquitin-like system mediates protein lipidation
- Biogenesis of the vacuole in Saccharomyces cerevisiae.
- Observation of the Yarrowia lipolytica peroxisome—vacuole dynamics by fluorescence microscopy with a single filter set
- GSA11 Encodes a Unique 208-kDa Protein Required for Pexophagy and Autophagy in Pichia pastoris *
- Cooperative Binding of the Cytoplasm to Vacuole Targeting Pathway Proteins, Cvt13 and Cvt20, to Phosphatidylinositol 3-Phosphate at the Pre-autophagosomal Structure Is Required for Selective Autophagy*
- The pre‐autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation
- Development of crystalline peroxisomes in methanol-grown cells of the yeast Hansenula polymorpha and its relation to environmental conditions
- Vac8p, a Vacuolar Protein with Armadillo Repeats, Functions in both Vacuole Inheritance and Protein Targeting from the Cytoplasm to Vacuole
- Sterol glucosyltransferases have different functional roles inPichia pastoris and Yarrowia lipolytica
- The Hansenula polymorpha PDD7 gene is essential for macropexophagy and microautophagy.
- Atg8 is Essential for Macropexophagy in Hansenula polymorpha
- Peroxisome Degradation by Microautophagy in Pichia pastoris: Identification of Specific Steps and Morphological Intermediates
- Paz2 and 13 other PAZ gene products regulate vacuolar engulfment of peroxisomes during micropexophagy
- Selective peroxisome degradation in Yarrowia lipolytica after a shift of cells from acetate/oleate/ethylamine into glucose/ammonium sulfate‐containing media
- Cvt9/Gsa9 Functions in Sequestering Selective Cytosolic Cargo Destined for the Vacuole
- Peroxisome degradation requires catalytically active sterol glucosyltransferase with a GRAM domain
- Biogenesis and metabolic significance of microbodies in urate-utilizing yeasts
Cited by
- Generation of Cubic Membranes by Controlled Homotypic Interaction of Membrane Proteins in the Endoplasmic Reticulum*
- Gss1 protein of the methylotrophic yeast Pichia pastoris is involved in glucose sensing, pexophagy and catabolite repression.
- Selective Autophagy: talking with the UPS
- Pexophagy in Pichia pastoris.
- Analysis of the molecular mechanism of autophagosome formation in yeast and zebrafish models
- Kinetoplastida: model organisms for simple autophagic pathways?
- Something old, something new: plant innate immunity and autophagy.
- Pathways for phospholipid deacylation in Saccharomyces cerevisiae and their impact on fatty acid trafficking and equilibrium
- Développement d'une méthode d'isolation des noyaux adaptée aux macrophages pour une caractérisation protéomique d'une nouvelle structure autophagique induite par le virus HSV-1
- Monitoring autophagy in yeast: the Pho8Delta60 assay.
- Bioprocess Studies of Biomass and Recombinant Protein Production by the Methylotrophic Yeast Pichia Pastoris
- Toxic mitochondrial effects induced by "red devil" chemotherapy
- Structural, biochemical, and cell biological characterization of RAB7 mutants that cause peripheral neuropathy
- Method for monitoring pexophagy in mammalian cells.
- Autophagy and organelle turnover in Leishmania major
- Methylotrophic yeasts near Ogataea (Hansenula) polymorpha: a proposal of Ogataea angusta comb. nov. and Candida parapolymorpha sp. nov.
- Biochemical methods to monitor autophagy-related processes in yeast.
- Monitoring organelle turnover in yeast using fluorescent protein tags.
- Membrane Origin for Autophagy
- Methods of plate pexophagy monitoring and positive selection for ATG gene cloning in yeasts.
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