Experimental Human Pneumococcal Carriage
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Summary
This work aims to develop an EHPC platform that is a safe and useful reproducible method that could be used to down-select candidate novel pneumococcal vaccines with prevention of carriage as a surrogate of vaccine induced immunity.
- Type
- article
- Published
- 2013-02-15
- Cited by
- 90
- References
- 14
- Access
- Open access
- OpenAlex
- https://openalex.org/W2071196463
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:10539597
Keywords
Carriage, Medicine, Biology, Microbiology, Virology
References
- Mediator release after nasal airway challenge with allergen.
- Experimental human pneumococcal carriage models for vaccine research.
- Establishment of a Streptococcus pneumoniae nasopharyngeal colonization model in adult mice.
- The estimation of the bactericidal power of the blood
- Human Nasal Challenge with Streptococcus pneumoniae Is Immunising in the Absence of Carriage
- Serotype Replacement and Multiple Resistance in Streptococcus pneumoniae After the Introduction of the Conjugate Pneumococcal Vaccine
- Declining serotype coverage of new pneumococcal conjugate vaccines relating to the carriage of Streptococcus pneumoniae in young children.
- The Immune Response to Pneumococcal Proteins during Experimental Human Carriage
- Serotype replacement in disease following pneumococcal vaccination: A discussion of the evidence
- Comparison between nasopharyngeal swab and nasal wash, using culture and PCR, in the detection of potential respiratory pathogens
- Report from a WHO working group: standard method for detecting upper respiratory carriage of Streptococcus pneumoniae
Cited by
- The Effects of Temperate Phage on Streptococcus Pneumoniae During Colonization
- Genetic stability of pneumococcal isolates during 35 days of human experimental carriage
- Modulation of nasopharyngeal innate defenses by viral coinfection predisposes individuals to experimental pneumococcal carriage
- Nutrition, immunity and human health
- Bronchoalveolar Lavage (BAL) for Research; Obtaining Adequate Sample Yield
- Experimental Human Pneumococcal Carriage Augments IL-17A-dependent T-cell Defence of the Lung
- Controlled human infection and rechallenge with Streptococcus pneumoniae reveals the protective efficacy of carriage in healthy adults.
- Impact of Experimental Human Pneumococcal Carriage on Nasopharyngeal Bacterial Densities in Healthy Adults
- Density and duration of pneumococcal carriage is maintained by transforming growth factor β1 and T regulatory cells.
- The adult nasopharyngeal microbiome as a determinant of pneumococcal acquisition
- Density and duration of experimental human pneumococcal carriage
- Pneumococcal Colonization Rates in Patients Admitted to a United Kingdom Hospital with Lower Respiratory Tract Infection: a Prospective Case-Control Study
- Pneumococcal colonization and invasive disease studied in a porcine model
- Polysaccharide-Specific Memory B Cells Predict Protection against Experimental Human Pneumococcal Carriage.
- Neuraminidase A-Exposed Galactose Promotes Streptococcus pneumoniae Biofilm Formation during Colonization
- Agglutination by anti-capsular polysaccharide antibody is associated with protection against experimental human pneumococcal carriage
- Composition and immunological significance of the upper respiratory tract microbiota
- Novel Analysis of Immune Cells from Nasal Microbiopsy Demonstrates Reliable, Reproducible Data for Immune Populations, and Superior Cytokine Detection Compared to Nasal Wash
- From Immunologically Archaic to Neoteric Glycovaccines
- The Type I Restriction Modification System SpnIII of Streptococcus pneumoniae
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