Jumping on the Train of Personalized Medicine: A Primer for Non-Geneticist Clinicians: Part 1. Fundamental Concepts in Molecular Genetics
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Summary
A series of three reviews to help non-geneticist clinicians get ready for the major breakthroughs that are likely to occur in the coming years in the fast-moving field of personalized medicine.
- Type
- article
- Published
- 2014-05-01
- Cited by
- 11
- References
- 51
- Access
- Open access
- OpenAlex
- https://openalex.org/W2070954740
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:401799
Keywords
Geneticist, International HapMap Project, Personalized medicine, Genetics, Biology
References
- Delivery of genomic medicine for common chronic adult diseases: a systematic review.
- Association within a family of a balanced autosomal translocation with major mental illness.
- Patterns of linkage disequilibrium in the human genome
- Predictive, personalized, preventive, participatory (P4) cancer medicine
- Performance of Genotype Imputations Using Data from the 1000 Genomes Project
- New from NPG: Genome-wide association study identifies five new schizophrenia loci
- Quality and completeness of SNP databases
- The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerases
- Human DNA Repair Genes
- Genomics. 1000 Genomes Project gives new map of genetic diversity.
- 1000 genomes: a world of variation.
- Cytogenetic findings in 250 schizophrenics: evidence confirming an excess of the X chromosome aneuploidies and pericentric inversion of chromosome 9.
- Regulation of chromatin structure via histone post-translational modification and the link to carcinogenesis
- The new cytogenetics: blurring the boundaries with molecular biology
- On the origin of mitochondria: a genomics perspective.
- Exome sequencing and the genetic basis of complex traits
- A history of microarrays in biomedicine
- Apolipoprotein E (APOE) allele distribution in the world. Is APOE*4 a ‘thrifty’ allele?
- Exome sequencing as a tool for Mendelian disease gene discovery
- Generations of sequencing technologies.
Cited by
- From big data analysis to personalized medicine for all: challenges and opportunities
- Genetics: A Window into the Biology of the Mind
- Encouraging physician adoption of genetic testing for precision medicine.
- On the origin of obesity: identifying the biological, environmental and cultural drivers of genetic risk among human populations
- Pathology, proteomics and the pathway to personalised medicine
- From systems biology to P4 medicine: applications in respiratory medicine
- BIG DATA ANALYSIS IN REHABILITATION TREATMENT
- Enhancing portability of trans-ancestral polygenic risk scores through tissue-specific functional genomic data integration
- Pharmacogenetics of Psoriasis Treatment
- Effects of Genetic Variability in Dopaminergic Pathway on Treatment Response in Parkinson’s Disease
- Enhancing Portability of Trans-Ancestral Polygenic Risk Scores through Tissue-Specific Functional Genomic Data Integration
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