Performance of Genotype Imputations Using Data from the 1000 Genomes Project
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Summary
1KG-based imputation can increase the opportunity to discover significant associations for SNPs across the allele frequency spectrum, and it is expected that later versions of the 1KG Project will provide even better imputation performance.
- Type
- article
- Published
- 2011-12-30
- Cited by
- 42
- References
- 35
- Access
- Open access
- OpenAlex
- https://openalex.org/W1989743336
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:7972387
Keywords
International HapMap Project, Imputation (statistics), 1000 Genomes Project, Single-nucleotide polymorphism, Haplotype
References
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- The Wellcome Trust Case Control Consortium, U.K.
- Utilizing Genotype Imputation for the Augmentation of Sequence Data
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- Genotype imputation for genome-wide association studies
- Integrating common and rare genetic variation in diverse human populations
- Variants within the immunoregulatory CBLB gene are associated with Multiple Sclerosis
- Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
- Practical aspects of imputation-driven meta-analysis of genome-wide association studies.
- The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data.
- A second generation human haplotype map of over 3.1 million SNPs
Cited by
- The future for genetic studies in reproduction
- Genomic and transcriptomic predictors of triglyceride response to regular exercise
- Genome-wide association analysis on normal hearing function identifies PCDH20 and SLC28A3 as candidates for hearing function and loss
- Improving accuracy of rare variant imputation with a two-step imputation approach
- Genotype-Based Score Test for Association Testing in Families
- Lupus risk variants in the PXK locus alter B-cell receptor internalization
- Imputation of the Rare HOXB13 G84E Mutation and Cancer Risk in a Large Population-Based Cohort
- Performance of Genotype Imputation for Low Frequency and Rare Variants from the 1000 Genomes
- Genome‐wide association studies of atopic dermatitis
- Assessment of Genotype Imputation Performance Using 1000 Genomes in African American Studies
- One Thousand Genomes Imputation in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium Aggressive Prostate Cancer Genome-wide Association Study
- Genome-Wide Association Studies of Allergic Diseases.
- Jumping on the Train of Personalized Medicine: A Primer for Non-Geneticist Clinicians: Part 1. Fundamental Concepts in Molecular Genetics
- Integrative pathway analysis of a genome-wide association study of (V)O(2max) response to exercise training.
- A pruning strategy of reference panels for fast SNP genotype imputation
- Evaluation of the Metabochip Genotyping Array in African Americans and Implications for Fine Mapping of GWAS-Identified Loci: The PAGE Study
- Genotype Imputation for Latinos Using the HapMap and 1000 Genomes Project Reference Panels
- Genotype Imputation for African Americans using data from HapMap Phase II versus 1000 Genomes Projects
- Imputation of rare variants in next generation association studies
- Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility
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