Metabolic and Hemodynamic Effects of Metformin and Glibenclamide in Normotensive NIDDM Patients
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Summary
In normotensive NIDDM patients, treatment with metformin was associated with greater reductions in body weight, plasma total cholesterol concentration, and erect diastolic blood pressure, whereas the systemic vascular resistance index increased after treatment with glibenclamide.
- Type
- article
- Published
- 1993-07-01
- Cited by
- 87
- References
- 16
- OpenAlex
- https://openalex.org/W2070771890
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:23002246
Keywords
Medicine, Glibenclamide, Metformin, Blood pressure, Internal medicine
References
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- Comparison of weight reduction with metoprolol in treatment of hypertension in young overweight patients.
- Treating insulin resistance in hypertension with metformin reduces both blood pressure and metabolic risk factors
- Failure of weight reduction to reduce mildly elevated blood pressure: a randomized trial.
- Effect of Metformin on Carbohydrate and Lipoprotein Metabolism in NIDDM Patients
- Comparison and reproducibility of transthoracic bioimpedance and dual beam Doppler ultrasound measurement of cardiac function in healthy volunteers.
- Fructosamine measurements in serum and plasma.
- Voltage-dependent ATP-sensitive potassium channels of skeletal muscle membrane
- The two-period cross-over clinical trial.
- Arterial dilations in response to calcitonin gene-related peptide involve activation of K+ channels
Cited by
- Insulin resistance, impaired glucose tolerance and non-insulin-dependent diabetes, pathologic mechanisms and treatment: current status and therapeutic possibilities.
- Metformin: old wine in new bottle--evolving technology and therapy in diabetes.
- Gliquidone versus metformin: differential effects on aorta in streptozotocin induced diabetic rats
- Vascular effects of glibenclamide vs. glimepiride and metformin in Type 2 diabetic patients
- Insulin Treatment in Type 2 Diabetes
- EFECTOS DE METFORMINA SOBRE LOS NIVELES DE NITROOXIDACIÓN EN PACIENTES HIPERTENSOS CON SÍNDROME METABÓLICO
- Safety, tolerability, and efficacy of metformin extended-release oral antidiabetic therapy in patients with type 2 diabetes: An observational trial in Asia
- A Review of Metabolic and Cardiovascular Effects of Oral Antidiabetic Agents: Beyond Glucose-Level Lowering
- Effects of adrenergic, cholinergic and ganglionic blockade on acute depressor responses to metformin in spontaneously hypertensive rats.
- Risk of fatal and nonfatal lactic acidosis with metformin use in type 2 diabetes mellitus.
- A Risk-Benefit Assessment of Metformin in Type 2 Diabetes Mellitus
- Weight loss in patients with diabetes treated with a metformin-sulfonylurea combination in comparison with twice-daily mixed insulin.
- Exploiting complementary therapeutic strategies for the treatment of type II diabetes and prevention of its complications.
- Metabolic and haemodynamic effects of metformin in patients with type 2 diabetes mellitus and hypertension
- Vascular effects of metformin. Possible mechanisms for its antihypertensive action in the spontaneously hypertensive rat.
- James Young Simpson, 7 June 1811
- Metformin-inclusive therapy reduces the risk of stroke in patients with diabetes: a 4-year follow-up study.
- Lipids and Diabetes Mellitus: A Review of Therapeutic Options
- Effects of metformin on tyrosine kinase activity, glucose transport, and intracellular calcium in rat vascular smooth muscle.
- Combined metformin and insulin therapy for patients with type 2 diabetes mellitus.
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