Schwann Cells and Deleted in Colorectal Carcinoma Direct Regenerating Motor Axons Towards Their Original Path
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Summary
Using live-cell imaging in zebrafish, this work visualize for the first time how in response to nerve transection distal Schwann cells change morphology as axons fragment, and how Schwann cell morphology reverses once regenerating growth cones have crossed the injury site and have grown along distalSchann cells outlining the original nerve path.
- Type
- article
- Published
- 2014-10-29
- Cited by
- 68
- References
- 84
- Access
- Open access
- OpenAlex
- https://openalex.org/W2070381140
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:17214115
Keywords
Schwann cell, Regeneration (biology), Biology, Neuroscience, Axon
References
- Regulation of netrin-1a expression by hedgehog proteins.
- Degeneration and regeneration of the nervous system
- Neurobiology of Peripheral Nerve Regeneration
- Mutual attraction between emigrant cells from transected denervated nerve.
- Evaluating the role of Netrin-1 during the early phase of peripheral nerve regeneration using the mouse median nerve model
- Identified motoneurons and their innervation of axial muscles in the zebrafish
- Zebrafish pigmentation mutations and the processes of neural crest development.
- Influences of the glial environment on the elongation of axons after injury: transplantation studies in adult rodents.
- Development and axonal outgrowth of identified motoneurons in the zebrafish
- Wallerian degeneration in the peripheral nervous system: participation of both Schwann cells and macrophages in myelin degradation
- c-Jun Reprograms Schwann Cells of Injured Nerves to Generate a Repair Cell Essential for Regeneration
- Negative regulation of myelination: Relevance for development, injury, and demyelinating disease
- Expression of neurotrophins in skeletal muscle: Quantitative comparison and significance for motoneuron survival and maintenance of function
- Neuronal Neuregulin 1 type III directs Schwann cell migration
- The metalloproteinase inhibitor Reck is essential for zebrafish DRG development
- Genetic dissection of neural circuits by Tol2 transposon-mediated Gal4 gene and enhancer trapping in zebrafish
- Netrin-1 and peripheral nerve regeneration in the adult rat.
- X-irradiation impairs regeneration of peripheral nerve across a gap
- Isolated satellite cells of a peripheral nerve direct the growth of regenerating frog axons
- The challenges and beauty of peripheral nerve regrowth
Cited by
- The Scales and Tales of Myelination: using zebrafish and mouse to study myelinating glia
- Past, Present, and Future of Nerve Conduits in the Treatment of Peripheral Nerve Injury
- The lh3 glycosyltransferase directs target-selective peripheral nerve regeneration
- Learning to swim, again: Axon regeneration in fish.
- You-Gui pills promote nerve regeneration by regulating netrin1, DCC and Rho family GTPases RhoA, Racl, Cdc42 in C57BL/6 mice with experimental autoimmune encephalomyelitis.
- Molecular Analysis of Target Specific Peripheral Nerve Regeneration
- The multicellular complexity of peripheral nerve regeneration.
- Pulsed magnetic field promotes proliferation and neurotrophic genes expression in Schwann cells in vitro.
- Analysis of myelinated axon formation in zebrafish
- Role of Netrin-1 Signaling in Nerve Regeneration
- Evolution of the functionally conserved DCC gene in birds
- Perineurial Glial Plasticity and the Role of TGF-β in the Development of the Blood–Nerve Barrier
- A small molecule screen identifies in vivo modulators of peripheral nerve regeneration in zebrafish
- Directed Differentiation of Human Bone Marrow Stromal Cells to Fate-Committed Schwann Cells
- Neuromuscular Synaptic Proteins In Development And Regeneration
- Live Imaging of Schwann Cell Development in Zebrafish.
- Transcriptomic Landscapes of Immune Response and Axonal Regeneration by Integrative Analysis of Molecular Pathways and Interactive Networks Post-sciatic Nerve Transection
- The synaptic receptor Lrp4 promotes peripheral nerve regeneration
- Linking wound response and inflammation to regeneration in the zebrafish larval fin.
- Axonal fusion: An alternative and efficient mechanism of nerve repair
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