Neuronal Neuregulin 1 type III directs Schwann cell migration
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Summary
It is demonstrated that zebrafish Neuregulin 1 (Nrg1) type III, which signals through ErbB receptors, controls Schwann cell migration in addition to its previously known roles in proliferation and myelination.
- Type
- article
- Published
- 2011-11-01
- Cited by
- 93
- References
- 60
- Access
- Open access
- OpenAlex
- https://openalex.org/W1967959203
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:2025012
Keywords
Biology, Neuregulin, Schwann cell, Neuregulin 1, Cell biology
References
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- Mechanisms of axon ensheathment and myelin growth
- Identification of Heregulin, a Specific Activator of p185erbB2
- Soluble neuregulin-1 has bi-functional, concentration-dependent effects on Schwann cell myelination
- fork head domain genes in zebrafish
- Schwann cells express NDF and SMDF/n-ARIA mRNAs, secrete neuregulin, and show constitutive activation of erbB3 receptors: evidence for a neuregulin autocrine loop.
- KBP is essential for axonal structure, outgrowth and maintenance in zebrafish, providing insight into the cellular basis of Goldberg-Shprintzen syndrome
- Targeting neural circuitry in zebrafish using GAL4 enhancer trapping
- A selective Sema3A inhibitor enhances regenerative responses and functional recovery of the injured spinal cord
- Integrity of developing spinal motor columns is regulated by neural crest derivatives at motor exit points.
- Protein Kinase A-mediated Gating of Neuregulin-dependent ErbB2-ErbB3 Activation Underlies the Synergistic Action of cAMP on Schwann Cell Proliferation*
- ErbB Signaling has a Role in Radial Sorting Independent of Schwann Cell Number
- Migration and function of a glial subtype in the vertebrate peripheral nervous system.
- Neuregulin-1 type III determines the ensheathment fate of axons.
- Axon-induced mitogenesis of human Schwann cells involves heregulin and p185erbB2.
Cited by
- Myoendothelial Contacts, Gap Junctions, and Microdomains: Anatomical Links to Function?
- Repulsive Epithelial Cues Direct Glial Migration along the Nerve.
- New insights into signaling during myelination in zebrafish
- Rôle des voies Wnt dans la régulation des gènes de la myéline et le cytosquelette des cellules de Schwann
- The N-terminal cytoplasmic domain of neuregulin 1 type III is intrinsically disordered
- GPR50, a potential factor involved in psychiatric disorders interacts with Alzheimer’s disease-related protein β- secretase (BACE1)
- Repulsive migration of schwann cells induced by slit‐2 through Ca2+‐dependent RhoA‐Myosin signaling
- Nanoparticles carrying neurotrophin-3-modified Schwann cells promote repair of sciatic nerve defects
- Neuroblastoma in dialog with its stroma: NTRK1 is a regulator of cellular cross-talk with Schwann cells
- The Scales and Tales of Myelination: using zebrafish and mouse to study myelinating glia
- Regulated intramembrane proteolysis of NRG1 type III dediates postnatal peripheral myelination
- Cellular Interactions During Motor Nerve Regeneration
- New Insights on Schwann Cell Development
- Schwann cells migrate along axons in the absence of GDNF signaling
- Dual Cleavage of Neuregulin 1 Type III by BACE1 and ADAM17 Liberates Its EGF-Like Domain and Allows Paracrine Signaling
- Molecular control of Schwann cell migration along peripheral axons
- Links between Schwann cells and melanocytes in development and disease
- Intrinsic Migratory Properties of Cultured Schwann Cells Based on Single-Cell Migration Assay
- Schwann Cells and Deleted in Colorectal Carcinoma Direct Regenerating Motor Axons Towards Their Original Path
- Loss of Bace2 in zebrafish affects melanocyte migration and is distinct from Bace1 knock out phenotypes
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