Potential clinical uses of laser scan microscopy.
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Summary
Preliminary data indicate that the higher light sensitivity of CLSM allows detection of low amounts of proto-oncogene mRNA which are minimally detectable by LM, which could lead to more refined therapeutic indications.
- Type
- article
- Published
- 1987-08-15
- Cited by
- 27
- References
- 14
- OpenAlex
- https://openalex.org/W2070011295
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:40439319
Keywords
Microscopy, Confocal laser scanning microscopy, Materials science, Confocal microscopy, Laser light
References
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- Sensitive detection of hybridocytochemical results by means of reflection-contrast microscopy.
- Confocal scanning light microscopy with high aperture immersion lenses
- The Genetic Analysis of Malignancy
Cited by
- Nonradioactive RNA in situ hybridization detection of human papillomavirus 16-E7 transcripts in squamous cell carcinomas of the uterine cervix using confocal laser scan microscopy.
- Konfokal Mikroskobi ve İn Vivo Oftalmik Kullanımı
- Handbook of Biological Confocal Microscopy
- Syphilis superinfection activates expression of human immunodeficiency virus I in latently infected rabbits.
- Highly sensitive, specific, and stable new fluorescent DNA stains for confocal laser microscopy and image processing of normal paraffin sections.
- Subcellular visualization of light microscopic specimens by laser scanning microscopy and computer analysis: a new application of image analysis.
- Quantification by laser scan microscopy of intracellular doxorubicin distribution.
- THREE‐DIMENSIONAL CONFOCAL LASER SCANNING DNA PLOIDY CYTOMETRY IN THICK HISTOLOGICAL SECTIONS
- Application research of laser scanning microscope for early diagnosis of tumors
- Confocal DNA cytometry: a contour-based segmentation algorithm for automated three-dimensional image segmentation.
- Quantification of biotinylated RNA probes for in situ hybridization using chemiluminescence
- Reproducibility of mean nuclear volume and correlation with mean nuclear area in breast cancer: an investigation of various sampling schemes.
- In vitro effects and localisation of the photosensitizers m‐THPC and m‐THPC MD on carcinoma cells of the human breast (MCF‐7) and chinese hamster fibroblasts (V‐79)
- Human immunodeficiency virus (HIV) transcripts identified in HIV-related psoriasis and Kaposi's sarcoma lesions.
- Design and application of a computer‐controlled confocal scanning differential polarization microscope
- Confocal laser microscopy and image processing for three-dimensional microscopy: technical principles and an application to breast cancer.
- Detection of low copy numbers of HPV DNA by fluorescent in situ hybridization combined with confocal microscopy as an alternative to in situ polymerase chain reaction.
- Three-dimensional computerised analysis of epithelial cell proliferation in the gastrointestinal tract.
- A light microscopy, scanning electron microscopy, and laser scanning microscopy analysis of retrieved blade implants after 7 to 20 years of clinical function. A report of 3 cases.
- Lack of expression of HLA-B27 gene in transgenic mouse trophoblast. Conserved genetic pressures underlying extra-embryonic development
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