Mass-spectrometry-based draft of the human proteome
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Summary
A mass-spectrometry-based draft of the human proteome and a public, high-performance, in-memory database for real-time analysis of terabytes of big data, called ProteomicsDB are presented, which enables navigation of proteomes, provides biological insight and fosters the development of proteomic technology.
- Type
- article
- Published
- 2014-05-28
- Cited by
- 1,825
- References
- 47
- OpenAlex
- https://openalex.org/W2069860553
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:4467721
Keywords
Proteome, Human proteome project, Computational biology, Proteomics, Proteogenomics
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- Regulatory Implications of Non-Trivial Splicing: Isoform 3 of Rab1A Shows Enhanced Basal Activity and Is Not Controlled by Accessory Proteins.
- Proteogenomics: Integrating Next-Generation Sequencing and Mass Spectrometry to Characterize Human Proteomic Variation
- The Size of the Human Proteome: The Width and Depth
- Characterization of human pineal gland proteome.
- A proteogenomic approach for protein-level evidence of genomic variants in cancer cells
- The challenges with the validation of research antibodies
- Mass spectrometry-based proteomics in cancer research
- Programming of Cell Resistance to Genotoxic and Oxidative Stress
- Helicobacter pylori induces direct activation of the lymphotoxin beta receptor and non-canonical nuclear factor-kappa B signaling.
- Immunoregulatory functions and the therapeutic implications of GARP-TGF-β in inflammation and cancer
- A Cetuximab-Mediated Suicide System in Chimeric Antigen Receptor–Modified Hematopoietic Stem Cells for Cancer Therapy
- High-throughput protein analysis using mass spectrometry-based methods
- Computational Assessment of Single-Molecule Protein Sequencing
- Mutationsprofile von Tumoren jenseits von Organ- und Gewebespezifität
- A Field-Proven Yeast Two-Hybrid Protocol Used to Identify Coronavirus–Host Protein–Protein Interactions
- Chemical Proteomics Uncovers EPHA2 as a Mechanism of Acquired Resistance to Small Molecule EGFR Kinase Inhibition.
- Distributed and interactive visual analysis of omics data.
- Genomic modulators of gene expression in human neutrophils
- Towards integrative structural mass spectrometry: Benefits from hybrid approaches.
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