Major glycoprotein antigens that induce antibodies in AIDS patients are encoded by HTLV-III.
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Summary
It is hypothesized that gp160 and gp120 represent the major species of virus-encoded envelope gene products for HTLV-III.
- Type
- article
- Published
- 1985-05-31
- Cited by
- 558
- References
- 29
- OpenAlex
- https://openalex.org/W2069851285
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:23090843
Keywords
Glycoprotein, Virology, Open reading frame, Antibody, Virus
References
- Complete nucleotide sequence of the AIDS virus, HTLV-III
- Characterization of the reverse transcriptase from a new retrovirus (HTLV) produced by a human cutaneous T-cell lymphoma cell line.
- Frequent detection and isolation of cytopathic retroviruses (HTLV-III) from patients with AIDS and at risk for AIDS.
- Antibodies to human T-cell leukemia virus membrane antigens (HTLV-MA) in hemophiliacs.
- Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS).
- Virus envelope protein of HTLV-III represents major target antigen for antibodies in AIDS patients.
- Determination of protein primary structure by radiochemical techniques.
- A new subtype of human T-cell leukemia virus (HTLV-II) associated with a T-cell variant of hairy cell leukemia.
- Serological analysis of a subgroup of human T-lymphotropic retroviruses (HTLV-III) associated with AIDS.
- Detection, isolation, and continuous production of cytopathic retroviruses (HTLV-III) from patients with AIDS and pre-AIDS.
- Sequence of the envelope glycoprotein gene of type II human T lymphotropic virus.
- Transfusion-associated AIDS: serologic evidence of human T-cell leukemia virus infection of donors.
- Antigens on HTLV-infected cells recognized by leukemia and AIDS sera are related to HTLV viral glycoprotein.
- Sequence homology and morphologic similarity of HTLV-III and visna virus, a pathogenic lentivirus.
- Trans-acting transcriptional regulation of human T-cell leukemia virus type III long terminal repeat.
- Alteration of T-cell functions by infection with HTLV-I or HTLV-II.
- Molecular characterization of human T-cell leukemia (lymphotropic) virus type III in the acquired immune deficiency syndrome.
- Molecular cloning and characterization of the HTLV-III virus associated with AIDS
- Aetiology of AIDS—antibodies to human T-cell leukaemia virus (type III) in haemophiliacs
- Isolation and transmission of human retrovirus (human t-cell leukemia virus).
Cited by
- Monoclonal Antibodies to HTLV-III451 gp41: Delineation of an Immunoreactive Conserved Epitope in the Transmembrane Region of Divergent Isolates of HIV-1
- AIDS, Portugal, and Africa.
- Antiserum to a synthetic peptide recognizes the HTLV-III envelope glycoprotein.
- Transfusion-acquired human immunodeficiency virus infection among immunocompromised persons.
- Probing the structure of the human immunodeficiency virus surface glycoprotein gp120 with a panel of monoclonal antibodies
- Antigenic properties of a transport-competent influenza HA/HIV Env chimeric protein.
- Mechanism of HIV-1 entry into CD4+ T cells.
- STUDIES OF THE DIMERIZATION AND PACKAGING SIGNALS IN HIV-2 RNA
- Transfusion-acquired HIV infection among immunocompromised hosts.
- The ectodomain of HIV‐1 env subunit gp41 forms a soluble, alpha‐helical, rod‐like oligomer in the absence of gp120 and the N‐terminal fusion peptide.
- Immunogenicity of synthetic peptides corresponding to various epitopes of the human immunodeficiency virus envelope protein.
- Development of Broadly Reactive HIV-1/AIDS Virus-like Particle Vaccines
- Human cell lines stably expressing HIV env and tat gene products.
- Development of a binding assay between the HIV-1 envelope protein (gp120) and coreceptors CCR5/CXCR4 by Surface Plasmon Resonance : Screening and optimization of viral entry inhibitors
- Characterisation of llama antibody fragments able to act as HIV-1 entry inhibitors
- The chronology of AIDS research
- Role of the human immunodeficiency virus type I envelope glycoprotein in cytopathic effect.
- Virus and host determinants of HIV-1 infection and AIDS pathogenesis
- Inhibition of HIV-1 and HSV-2 infection by glycosaminoglycan mimetics
- Antibodies to human T-cell leukemia virus type III in hemophiliacs from Spain.
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