Mode of action of the antiprion drugs 6AP and GA on ribosome assisted protein folding.

Keywords

Ribosome, Ribosomal protein, Protein folding, Eukaryotic Ribosome, Biochemistry

References

• Mutations in domain V of the 23S ribosomal RNA of Bacillus subtilis that inactivate its protein folding property in vitro.Nele De Belie, Sybrand van der Zwaag, Elke Gruyaert — 2002
• Reconstitution of denatured E. coli alkaline phosphatase with E. coli ribosome.Biswadip Das, Chetna Gupta — 1992
• Refolding of denatured lactate dehydrogenase by Escherichia coli ribosomes.Subrata Chattopadhyay, Biswadip Das, Asit Kumar Bera — 1994
• The purification and properties of carbonic anhydrases from guinea-pig erythrocytes and mucosae of the gastrointestinal tract.M. J. Carter, D. S. Parsons — 1970
• Reactivation of denatured fungal glucose 6-phosphate dehydrogenase and E. coli alkaline phosphatase with E. coli ribosome.Biswadip Das, Subrata Chattopadhyay, Chanchal Das Gupta — 1992
• In vitro protein folding by ribosomes from Escherichia coli, wheat germ and rat liver: the role of the 50S particle and its 23S rRNA.Biswadip Das, Subrata Chattopadhyay, Aloke Kumar Bera — 1996
• Purification and properties of human erythrocyte carbonic anhydrases.J Armstrong, Dirck V. Myers, Jacob A. Verpoorte — 1966
• The folding of dimeric cytoplasmic malate dehydrogenase. Equilibrium and kinetic studies.Suparna Sanyal, Debasish Bhattacharyya, Chanchal Das Gupta — 2002
• THE CLINICAL ASPECTS OF AMYLOIDOSISEli Moschcowitz — 1936
• Antiprion drugs 6-aminophenanthridine and guanabenz reduce PABPN1 toxicity and aggregation in oculopharyngeal muscular dystrophyNicolas Barbezier, Aymeric Chartier, Yannick Bidet — 2011
• Ribosome–DnaK interactions in relation to protein foldingJaydip Ghosh, Arunima Basu, Saumen Pal — 2003
• The protein product of the het-s heterokaryon incompatibility gene of the fungus Podospora anserina behaves as a prion analog.Virginie Coustou, Carol Deleu, Sven J. Saupe — 1997
• Antihypertensive Drug Guanabenz Is Active In Vivo against both Yeast and Mammalian PrionsDéborah Tribouillard‐Tanvier, Vincent Béringue, Nathalie Desban — 2008
• Reactivation of denatured proteins by 23S ribosomal RNA: role of domain V.Subrata Chattopadhyay, Biswadip Das, Chandan Dasgupta — 1996
• A Single Step Synthesis of 6‐Aminophenanthridines from Anilines and 2‐Chlorobenzonitriles.Fabienne Gug, Stéphane Bach, Marc Blondel — 2004
• Novel proteinaceous infectious particles cause scrapie.Stanley B. Prusiner — 1982
• Protein Folding Activity of Ribosomal RNA Is a Selective Target of Two Unrelated Antiprion DrugsDéborah Tribouillard‐Tanvier, Suzana Dos Reis, Fabienne Gug — 2008
• Using budding yeast to screen for anti-prion drugs.Déborah Tribouillard‐Tanvier, Stéphane Bach, Fabienne Gug — 2006
• Ribosome-mediated Folding of Partially Unfolded Ricin A-chain*Richard H. Argent, Andrew M. Parrott, Philip J. Day — 2000
• Prion protein selectively binds copper(II) ions.Johannes Stöckel, Jiri Safar, Andrew C. Wallace — 1998

Cited by

• Using Saccharomyces cerevisiae to characterisethe in vivo effects of exposure to the prion-curingdrug Tacrine and the fungal metabolite gliotoxinJ. O’Brien — 2012
• The various facets of the protein‐folding activity of the ribosomeCécile Voisset, Sven J. Saupe, Marc Blondel — 2011
• Using yeast to model calcium-related diseases: example of the Hailey-Hailey disease.Cécile Voisset, Néstor García‐Rodríguez, April Birkmire — 2014
• The Antiprion Compound 6-Aminophenanthridine Inhibits the Protein Folding Activity of the Ribosome by Direct Competition*Yanhong Pang, Sriram Kurella, Cécile Voisset — 2013
• Spectroscopic and DFT studies on 6-aminophenanthridine and its derivatives provide insights in their activity towards ribosomal RNA.Debapriya Banerjee, Hakkim Vovusha, Yanhong Pang — 2014
• The Toll-Like Receptor Agonist Imiquimod Is Active against PrionsNassima Oumata, Phu hai Nguyen, Vincent Béringue — 2013
• Electronic structure and spectroscopic properties of 6-aminophenanthridine and its derivatives: Insights from density functional theoryHakkim Vovusha, Debapriya Banerjee, Nassima Oumata — 2015
• Structure-activity relationship study around guanabenz identifies two derivatives retaining antiprion activity but having lost α2-adrenergic receptor agonistic activity.Phu hai Nguyen, Hassan Hammoud, Sophie Halliez — 2014
• Protein Folding Activity of the Ribosome (PFAR) –– A Target for Antiprion CompoundsDebapriya Banerjee, Suparna Sanyal — 2014
• Mechanistic Insight into the Reactivation of BCAII Enzyme from Denatured and Molten Globule States by Eukaryotic Ribosomes and Domain V rRNAsBiprashekhar Chakraborty, S. Bhakta, Jayati Sengupta — 2016
• Protein Folding Activity of the Ribosome is involved in Yeast Prion PropagationMarc Blondel, Flavie Soubigou, Justine Evrard — 2016
• Sequestration of Ribosome during Protein Aggregate Formation: Contribution of ribosomal RNABani Kumar Pathak, Surojit Mondal, Senjuti Banerjee — 2017
• The double life of the ribosome: When its protein folding activity supports prion propagationCécile Voisset, Marc Blondel, Gary W. Jones — 2017
• Distinct modulatory role of RNA in the aggregation of the tumor suppressor protein p53 core domainPetar Stefanov Kovachev, Debapriya Banerjee, Luciana P. Rangel — 2017
• Guanabenz treatment improves Oculopharyngeal muscular dystrophy phenotypeAlberto Malerba, Fanny Roth, Pradeep Harish — 2018
• Pharmacological modulation of the ER stress response ameliorates oculopharyngeal muscular dystrophy.Alberto Malerba, Fanny Roth, Pradeep Harish — 2019
• RNA modulates aggregation of the recombinant mammalian prion protein by direct interactionPetar Stefanov Kovachev, Mariana P. B. Gomes, Yraima Cordeiro — 2019
• Ribosomal RNA Modulates Aggregation of the Podospora Prion Protein HET-sYanhong Pang, Petar Stefanov Kovachev, Suparna Sanyal — 2020
• A Closer Look at Estrogen Receptor Mutations in Breast Cancer and Their Implications for Estrogen and Antiestrogen ResponsesLéa Clusan, Pascale Le Goff, Gilles Flouriot — 2021
• The small compound Icerguastat reduces muscle defects in oculopharyngeal muscular dystrophy through the PERK pathway of the unfolded protein responseRima Naït-Saïdi, Aymeric Chartier, Emmanuelle Abgueguen — 2023

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