Developmental and regional expression in the rat brain and functional properties of four NMDA receptors.
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Summary
Recombinant binary NR1-NR2 channels show comparable Ca2+ permeabilities, but marked differences in voltage-dependent Mg2+ block and in offset decay time constants, which provide a basis for NMDA channel heterogeneity in the brain.
- Type
- article
- Published
- 1994-03-01
- Cited by
- 3,612
- References
- 32
- OpenAlex
- https://openalex.org/W2065169750
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:26733598
Keywords
NMDA receptor, Biology, Messenger RNA, Granule cell, Neuroscience
References
- Molecular machines integrate coincident synaptic signals.
- Selective loss of Purkinje and granule cell responsiveness to N-methyl-D-aspartate in rat cerebellum during development.
- Frequency‐dependent N‐methyl‐D‐aspartate receptor‐mediated synaptic transmission in rat hippocampus.
- Molecular characterization of the family of the N-methyl-D-aspartate receptor subunits.
- The differential expression of 16 NMDA and non-NMDA receptor subunits in the rat spinal cord and in periaqueductal gray
- Regional and developmental heterogeneity in splicing of the rat brain NMDAR1 mRNA
- High-efficiency transformation of mammalian cells by plasmid DNA.
- Channel kinetics determine the time course of NMDA receptor-mediated synaptic currents
- Developmental changes in distribution of NMDA receptor channel subunit mRNAs.
- Postnatal development of the chemosensitivity of rat cerebellar Purkinje cells to excitatory amino acids. An in vitro study.
- Flip and flop: a cell-specific functional switch in glutamate-operated channels of the CNS.
- Fast and slow components of unitary EPSCs on stellate cells elicited by focal stimulation in slices of rat visual cortex.
- Patterned activity, synaptic convergence, and the NMDA receptor in developing visual pathways.
- Molecular diversity of the NMDA receptor channel
- Magnesium gates glutamate-activated channels in mouse central neurones
- NMDA receptors in the visual cortex of young kittens are more effective than those of adult cats
- Preferential co-assembly of recombinant NMDA receptors composed of three different subunits.
- NMDA-receptor activation increases cytoplasmic calcium concentration in cultured spinal cord neurones
- Glutamate neurotoxicity and diseases of the nervous system.
- Physiological and pathophysiological roles of excitatory amino acids during central nervous system development.
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- Distinct N-Methyl—aspartate Receptor 2B Subunit Gene Sequences Confer Neural and Developmental Specific Expression*
- Physiological release of excitatory amino acids.
- NMDA receptor 2C subunit is selectively decreased by MK-801 in the entorhinal cortex.
- Transient Global Ischemia Alters NMDA Receptor Expression in Rat Hippocampus: Correlation with Decreased Immunoreactive Protein Levels of the NR2A/2B Subunits, and an Altered NMDA Receptor Functionality
- Functional consequences of NR2 subunit composition in single recombinant N-methyl-D-aspartate receptors.
- Susceptibility of adult rats to lead-induced changes in NMDA receptor complex function.
- Expression of NR1, NR2A‐D, and NR3 subunits of the NMDA receptor in the cerebral cortex and olfactory bulb of adult rat
- Topology of ionotropic glutamate receptors in brains of heterozygous and homozygous weaver mutant mice
- Update on the glutamatergic neurotransmitter system and the role of excitotoxicity in amyotrophic lateral sclerosis
- Large variability in synaptic N-methyl-D-aspartate receptor density on interneurons and a comparison with pyramidal-cell spines in the rat hippocampus.
- Recent advances in cerebellar granule cell migration
- Neural ECM and epilepsy.
- Selective loss of NMDA receptor NR1 subunit isoforms in Alzheimer's disease
- NMDA receptors in the anterior cingulate cortex mediate pain-related aversion.
- The excitoprotective effect of N‐methyl‐d‐aspartate receptors is mediated by a brain‐derived neurotrophic factor autocrine loop in cultured hippocampal neurons
- A Specific Role for NR2A-Containing NMDA Receptors in the Maintenance of Parvalbumin and GAD67 Immunoreactivity in Cultured Interneurons
- NR2B antagonists restrict spatiotemporal spread of activity in a rat model of cortical dysplasia.
- Obligatory role of NR2A for metaplasticity in visual cortex.
- Long-lasting NMDA receptor-mediated EPSCs in mouse striatal medium spiny neurons.
- The Regulation of Dendritic Spine Plasticity by EphB and N-methyl-D-aspartate Receptors Through Spatial Control Over Cofilin Activity in Mature Hippocampal Neurons
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