Effect of oxygen and endotoxin on lactate dehydrogenase release, 5‐hydroxytryptamine uptake, and antioxidant enzyme activities in endothelial cells
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Summary
Hyperoxia injures both pulmonary artery and aortic endothelial cells in culture and causes changes in the antioxidant enzyme profile that are similar in the two cell types; hyperoxia‐induced decreases in CAT activity and increases in SOD activity may be responsible for increased sensitivity of endothelial Cells to O2 toxicity.
- Type
- article
- Published
- 1985-02-01
- Cited by
- 59
- References
- 42
- OpenAlex
- https://openalex.org/W2063596745
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:36378700
Keywords
Hyperoxia, Lactate dehydrogenase, Antioxidant, Glutathione reductase, Superoxide dismutase
References
- Endotoxin-cell-membrane interactions leading to transmembrane signaling.
- Isolation and culture of pulmonary artery endothelial cells.
- Liposome-mediated augmentation of superoxide dismutase in endothelial cells prevents oxygen injury.
- Superoxide radical inhibits catalase.
- Properties and regulation of glutathione peroxidase.
- Biology of disease: free radicals and tissue injury.
- Protein measurement with the Folin phenol reagent.
- Pulmonary inflammation due to oxygen toxicity: involvement of chemotactic factors and polymorphonuclear leukocytes.
- Structural and biochemical changes in rat lungs occurring during exposures to lethal and adaptive doses of oxygen.
- Oxygen effect on lung cells.
- INTRAMITOCHONDRIAL FILAMENTOUS BODIES IN THE THICK LIMB OF HENLE OF THE RAT KIDNEY
- Expression of angiotensin‐converting enzyme activity in cultured pulmonary artery endothelial cells
- DEVELOPMENT OF FINE STRUCTURAL DAMAGE TO ALVEOLAR AND CAPILLARY LINING CELLS IN OXYGEN-POISONED RAT LUNGS
- The role of endotoxin in protection of adult rats from oxygen-induced lung toxicity.
- Effects of isolation and culture on prostaglandin synthesis by porcine aortic endothelial and smooth muscle cells
- Inhibition of angiotensin converting enzyme activity in cultured endothelial cells by hypoxia.
- Effects of culture conditions and hyperoxia on antioxidant enzymes in pig pulmonary artery and aortic endothelium.
- Enhanced rates of fluid pinocytosis during exponential growth and monolayer regeneration by cultured arterial endothelial cells
- Tumours of the Skin and other Delayed Effects of External Beta Irradiation of Mice Using 90Sr and 32P
- Vascular endothelial cells maintained in the absence of fibroblast growth factor undergo structural and functional alterations that are incompatible with their in vivo differentiated properties
Cited by
- Effect of plasma membrane fluidity on serotonin transport by endothelial cells.
- Hypoxia directly increases serotonin transport by porcine pulmonary artery endothelial cell plasma membrane vesicles.
- Normobaric pulmonary oxygen toxicity : experimental studies on the mechanism of the protective role of endotoxin and the role of surfactant.
- Nitrogen dioxide-induced changes in cell membrane fluidity and function.
- Age-dependent changes and interrelations of number of cells and biochemical parameters (glucose, triglycerides, TBARS, calcium, phosphorus) in cultured human vein endothelial cells.
- Effect of anoxia and reoxygenation on antioxidant enzyme activities in immortalized brain endothelial cells
- Augmentation of antioxidant enzymes in vascular endothelium.
- Engineering high-density endothelial cell monolayers on soft substrates.
- Plasma membrane fluidity measurements in intact endothelial cells: Effect of hyperoxia on fluorescence anisotropies of 1‐[4‐(trimethylamino)phenyl]‐6‐phenyl hexa‐1,3,5‐triene
- Effects of hyperoxia on microvascular cells in vitro
- Developmental aspects of experimental pulmonary oxygen toxicity.
- Normobaric Pulmonary Oxygen Toxicity
- The contribution of vascular endothelial xanthine dehydrogenase/oxidase to oxygen-mediated cell injury.
- Fatty acid supplementation protects pulmonary artery endothelial cells from oxidant injury.
- Effect of phospholipid acyl chain modulation on vitamin E incorporation into pulmonary artery endothelial cell membranes
- Endotoxin Induces Glutathione Reductase Activity in Lungs of Mice
- Hydrogen peroxide alters the physical state and function of the plasma membrane of pulmonary artery endothelial cells
- The effect of oxidant gases on membrane fluidity and function in pulmonary endothelial cells.
- Vascular effects of oxygen-derived free radicals.
- Mechanism of hydrogen peroxide-induced inhibition of sheep airway cilia.
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