Contribution of central neuroplasticity to pathological pain: review of clinical and experimental evidence

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Summary

This review examines the clinical and experimental evidence which points to a contribution of central Neurol plasticity to the development of pathological pain, and assesses the physiological, biochemical, cellular and molecular mechanisms that underlie plasticity induced in the central nervous system in response to noxious peripheral stimulation.

Type
review
Published
1993-03-01
Cited by
2,008
References
312
Access
Open access

Keywords

Pathological, Noxious stimulus, Neuroscience, Nociceptor, Neuroplasticity

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