Multiple effects of phorbol esters in the rat spinal dorsal horn
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Summary
Results suggest that in the rat spinal dorsal horn protein kinase C may have a role in controlling the release of putative excitatory and inhibitory neurotransmitters and may also be involved in the regulation of postsynaptic NMDA receptors.
- Type
- article
- Published
- 1989-10-01
- Cited by
- 155
- References
- 80
- Access
- Open access
- OpenAlex
- https://openalex.org/W1800713457
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:15264377
Keywords
Excitatory postsynaptic potential, Quisqualic acid, Neurotransmission, Chemistry, Glutamate receptor
References
- Activation of calcium and phospholipid-dependent protein kinase by diacylglycerol, its possible relation to phosphatidylinositol turnover.
- Calcium-dependent activation of a multifunctional protein kinase by membrane phospholipids.
- Heterogeneous localization of protein kinase C in rat brain: autoradiographic analysis of phorbol ester receptor binding
- Studies on a cyclic nucleotide-independent protein kinase and its proenzyme in mammalian tissues. II. Proenzyme and its activation by calcium-dependent protease from rat brain.
- Enhancement of adenylate cyclase activity in S49 lymphoma cells by phorbol esters. Putative effect of C kinase on alpha s-GTP-catalytic subunit interaction.
- Immunocytochemical localization of protein kinase C in identified neuronal compartments of rat brain
- Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.
- Phorbol esters: voltage-dependent effects on calcium-dependent action potentials of mouse central and peripheral neurons in cell culture
- Protein Kinase C Activators Enhance Transmission at the Squid Giant Synapse
- Phorbol esters mimic some cholinergic actions in hippocampal pyramidal neurons
- Correlation between inositol phospholipid hydrolysis and substance P receptors in rat CNS
- Studies and perspectives of protein kinase C.
- An activator of protein kinase C (phorbol‐12‐myristate‐13‐acetate) augments 2‐chloroadenosine‐elicited accumulation of cyclic AMP in guinea pig cerebral cortical particulate preparations
- Effects of phorbol ester on catecholamine secretion and protein phosphorylation in adrenal medullary cell cultures.
- Phorbol 12,13-dibutyrate enhances electrically stimulated neuromessenger release from rat dorsal hippocampal slices in vitro.
- Polyclonal antibodies to phospholipid/Ca2+-dependent protein kinase and immunocytochemical localization of the enzyme in rat brain.
- Effects of intracellular injections of phorbol ester and protein kinase C on cat spinal motoneurons in vivo.
- Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide dependent protein kinase and protein kinase C.
- The phorbol ester TPA increases the affinity of exocytosis for calcium in ‘leaky’ adrenal medullary cells
- Phorbol Ester Enhancement of Neurotransmitter Release from Rat Brain Synaptosomes
Cited by
- Phosphorylation and modulation of recombinant GluR6 glutamate receptors by cAMP-dependent protein kinase
- Effects of short-acting NMDA receptor antagonist MRZ 2/576 on morphine tolerance development in mice
- Differential expression and ser897 phosphorylation of striatal N-methyl-d-aspartate receptor subunit NR1 in animal models of Parkinson's disease.
- Modulation of excitatory synaptic transmission in the rat spinal dorsal horn
- The role of peptides in central sensitization.
- Release of endogenous amino acids with putative neurotransmitter function from the rat spinal dorsal horn in vitro--modulation by neuropeptides
- Synaptic transmission and plasticity in the spinal cord substantia gelatinosa: the role of GluR2, GluR5 and GluR6 glutamate receptor subunits
- Protéine kinase C γ et hypersensibilité mécanique trigéminale chez le rat
- Avaliação do potencial efeito antipsicótico da miricitrina em modelos animais
- Long-term potentiation and long-term depression of primary afferent neurotransmission in the rat spinal cord
- Protein kinase C modulates NMDA receptor trafficking and gating
- Substance P Modulates NMDA Responses and Causes Long-Term Protein Synthesis-Dependent Modulation of the Lamprey Locomotor Network
- Enhancement of the N-methyl-D-aspartate response in spinal dorsal horn neurons by cAMP-dependent protein kinase.
- Involvement of glutamatergic neurotransmission and protein kinase C in spinal plasticity and the development of chronic pain.
- Interaction of neuropeptides and excitatory amino acids in the rat superficial spinal dorsal horn.
- Two modes of exocytosis from synaptosomes are differentially regulated by protein phosphatase types 2A and 2B
- Modulation of amino acid-gated ion channels by protein phosphorylation.
- The effects of G‐protein and protein kinase inhibitors on the behavioral responses of rats to intradermal injection of capsaicin
- PSD‐95 eliminates Src‐induced potentiation of NR1/NR2A‐subtype NMDA receptor channels and reduces high‐affinity zinc inhibition
- Expression of splice variants of the NR1 subunit of the N‐methyl‐d‐aspartate receptor in the normal and injured rat spinal cord
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