Tumour stem cells and drug resistance
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Summary
Gaining a better insight into the mechanisms of stem-cell resistance to chemotherapy might lead to new therapeutic targets and better anticancer strategies.
- Type
- review
- Published
- 2005-04-01
- Cited by
- 3,733
- References
- 112
- OpenAlex
- https://openalex.org/W2062069198
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:22402588
Keywords
Stem cell, Cancer stem cell, Haematopoiesis, Cancer research, Drug resistance
References
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- Stem cells in normal breast development and breast cancer
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- The human ATP-binding cassette (ABC) transporter superfamily.
- The multidrug resistance transporter ABCG2 (breast cancer resistance protein 1) effluxes Hoechst 33342 and is overexpressed in hematopoietic stem cells.
- Therapeutic implications of cancer stem cells.
- Imatinib mesylate (STI571) inhibits growth of primitive malignant progenitors in chronic myelogenous leukemia through reversal of abnormally increased proliferation.
- Normal genetically mosaic mice produced from malignant teratocarcinoma cells.
- Bcrp1 gene expression is required for normal numbers of side population stem cells in mice, and confers relative protection to mitoxantrone in hematopoietic cells in vivo
Cited by
- Tumor dormancy and metastasis.
- Detection of putative cancer stem cells of the side population phenotype in human tumor cell cultures.
- Advances in Cancer Stem Cell Biology
- Suramin Increased Telomerase Activity in the C6 Glioma/Wistar Experimental Brain Tumor Model
- Cancer stem cells in human gastrointestinal cancers
- Enhanced Growth Inhibition of Hepatic Multicellular Tumor Spheroids by Lactosylated Poly(ethylene glycol)‐siRNA Conjugate Formulated in PEGylated Polyplexes
- Identification and characterization of tumorigenic liver cancer stem/progenitor cells.
- Hematopoietic stem cell transplantation in adults with acute myeloid leukemia.
- The search for cancer stem cells in hepatocellular carcinoma.
- Cellular immortality in brain tumours: an integration of the cancer stem cell paradigm.
- Cancer stem cells at the crossroads of current cancer therapy failures--radiation oncology perspective.
- 肺癌侧群细胞microRNA表达谱检测及初步分析
- Targeting the Wnt/β-catenin signaling pathway in human cancers
- Expression of glioma stem cell marker CD133 and O6-methylguanine-DNA methyltransferase is associated with resistance to radiotherapy in gliomas.
- Targeting carbonic anhydrase IX depletes breast cancer stem cells within the hypoxic niche
- Oncolytic virotherapy for malignant glioma: translating laboratory insights into clinical practice
- Probing the Hepatic Progenitor Cell in Human Hepatocellular Carcinoma
- The expression of aldehyde dehydrogenase 1 in invasive primary breast tumors and axillary lymph node metastases is associated with poor clinical prognosis.
- Tumor and its microenvironment: a synergistic interplay.
- Combining conventional chemotherapy and γδ T cell-based immunotherapy to target cancer-initiating cells
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