Oncolytic virotherapy for malignant glioma: translating laboratory insights into clinical practice
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Summary
The leading anti-glioma virotherapy approaches that are presently under preclinical and clinical evaluation are discussed and different delivery methods, in vivo virus behavior, fate, replication, intratumoral spread, activation of anti-tumor immune response, and targeting of glioma stem cells are reviewed.
- Type
- article
- Published
- 2013-02-25
- Cited by
- 25
- References
- 169
- Access
- Open access
- OpenAlex
- https://openalex.org/W23443138
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:6323991
Keywords
Computer science, Political science
References
- Histone Deacetylase Inhibitors Augment Antitumor Efficacy of Herpes-based Oncolytic Viruses.
- Active immunotherapy: oncolytic virus therapy using HSV-1.
- An adenovirus E1A mutant that demonstrates potent and selective systemic anti-tumoral efficacy
- Matrix metalloproteinases: a tail of a frog that became a prince
- Hurdles and Hopes for Cancer Treatment
- Human brain tumor transplantation into nude mice.
- A controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer
- Potential of the conditionally replicative adenovirus Ad5-Delta24RGD in the treatment of malignant gliomas and its enhanced effect with radiotherapy.
- Targeting Brain Tumor Stem Cells with Oncolytic Adenoviruses
- Reovirus and tumor oncolysis.
- Thymidine Kinase Gene Therapy for Human Malignant Glioma, Using Replication-Deficient Retroviruses or Adenoviruses
- Matrix metalloproteinases-1 and -8 improve the distribution and efficacy of an oncolytic virus.
- Reversible osmotic blood-brain barrier disruption in humans: implications for the chemotherapy of malignant brain tumors.
- Biodistribution of an oncolytic adenovirus after intracranial injection in permissive animals: a comparative study of Syrian hamsters and cotton rats
- Attenuated multi–mutated herpes simplex virus–1 for the treatment of malignant gliomas
- Reversible activation of c-Myc in skin: induction of a complex neoplastic phenotype by a single oncogenic lesion.
- Comparative evaluation of survivin, midkine, and CXCR4 promoters for transcriptional targeting of glioma gene therapy
- Glioma virotherapy: effects of innate immune suppression and increased viral replication capacity.
- Neural stem cells target intracranial glioma to deliver an oncolytic adenovirus in vivo
- Enhanced anti-tumor efficacy of low dose etoposide with oncolytic herpes simplex virus in human glioblastoma stem cell xenografts
Cited by
- Conjugation of pH-Responsive Nanoparticles to Neural Stem Cells Improves Intratumoral Therapy
- An armed, YB-1-dependent oncolytic adenovirus as a candidate for a combinatorial anti-glioma approach of virotherapy, suicide gene therapy and chemotherapeutic treatment
- Current status of gene therapy for brain tumors
- Strategies in Gene Therapy for Glioblastoma
- Gene therapy for malignant glioma
- Microglia and astrocytes attenuate the replication of the oncolytic vaccinia virus LIVP 1.1.1 in murine GL261 gliomas by acting as vaccinia virus traps
- MiR-215, an activator of the CTNNBIP1/β-catenin pathway, is a marker of poor prognosis in human glioma
- Development and characterization of a recombinant vesicular stomatitis virus (rvsv) for the treatment of glioblastoma
- Single dose GLP toxicity and biodistribution study of a conditionally replicative adenovirus vector, CRAd-S-pk7, administered by intracerebral injection to Syrian hamsters
- EXPLORING THE ANTITUMOR EFFECT OF VIRUS IN MALIGNANT GLIOMA
- Involvement of microRNA-1297, a new regulator of HMGA1, in the regulation of glioma cell growth in vivo and in vitro.
- Polymorphism in the IL4R gene and clinical features are associated with glioma prognosis
- Safe and Effective Treatment of Experimental Neuroblastoma and Glioblastoma Using Systemically Delivered Triple MicroRNA-Detargeted Oncolytic Semliki Forest Virus
- De-differentiation of glioma cells to glioma stem-like cells by therapeutic stress-induced HIF signaling in the recurrent GBM model
- The role of TNF-α inhibitor in glioma virotherapy: A mathematical model.
- Intraperitoneal Administration of Neural Stem Cell-Nanoparticle Conjugates Targets Chemotherapy to Ovarian Tumors
- A Comparative Study of Replication-Incompetent and -Competent Adenoviral Therapy-Mediated Immune Response in a Murine Glioma Model
- Treatment of glioma with virotherapy and TNF- α inhibitors: Analysis as a dynamical system
- Optimal Control for a Mathematical Model of Glioma Treatment with Oncolytic Therapy and TNF-α α Inhibitors
- A Critical Overview of Targeted Therapies for Glioblastoma
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