Lysophosphatidylcholine as a Ligand for the Immunoregulatory Receptor G2A
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Summary
It is shown that LPC is a high-affinity ligand for G2A, a lymphocyte-expressed G protein–coupled receptor whose genetic ablation results in the development of autoimmunity.
- Published
- 2001-07-27
- Cited by
- 331
- References
- 18
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:34608996
References
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- Lysophosphatidylcholine, a component of atherogenic lipoproteins, induces mononuclear leukocyte adhesion molecules in cultured human and rabbit arterial endothelial cells.
- Identification of a Molecular Target of Psychosine and Its Role in Globoid Cell Formation
- Identification of the serum factor required for in vitro activation of macrophages. Role of vitamin D3-binding protein (group specific component, Gc) in lysophospholipid activation of mouse peritoneal macrophages.
- Identification of a putative G protein-coupled receptor induced during activation-induced apoptosis of T cells.
- Cytokine Dysregulation Induced by Apoptotic Cells Is a Shared Characteristic of Murine Lupus1
- Atherosclerosis : Vascular biology
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- Development and selection of marginal zone B cells
- Regulation of immunity by lysosphingolipids and their G protein-coupled receptors.
- The multi-functional role of sphingosylphosphorylcholine.
- Migration to Apoptotic “Find-me” Signals Is Mediated via the Phagocyte Receptor G2A*
- G2A as a receptor for oxidized free fatty acids.
- Novel lysophosphoplipid receptors: their structure and function
- Bioactive lysophospholipids and mesangial cell intracellular signaling pathways: role in the pathobiology of kidney disease.
- Structure-activity relationship of lysophosphatidylcholines in HL-60 human leukemia cells.
- Apoptotic cells at the crossroads of tolerance and immunity.
- FT-IR spectroscopic analysis of normal and cancerous tissues of esophagus.
- Intracrine signaling through lipid mediators and their cognate nuclear G-protein-coupled receptors: a paradigm based on PGE2, PAF, and LPA1 receptors.
- Bioactive Lipid Signaling in Enteric Glia.
- The Macrophage as Therapeutic Target
- BIOLOGICAL FUNCTIONS OF THE NOVEL LYSOPHOSPHATIDIC ACID (LPA) RECEPTOR, LPA 4 /p2y9/GPR23
- The characterisation of a functional interaction between Ikaros and Foxp1 in pre-B-cells and acute lymphoblastic leukaemia
- Marginal zone B cell physiology and disease.
- Involvement of Group VIA Calcium-Independent Phospholipase A2 in Macrophage Engulfment of Hydrogen Peroxide-Treated U937 Cells1
- Noninvasive imaging of reporter gene expression in living subjects.
- AUTOIMMUNE RESPONSES TO ATHEROSCLEROTIC
- Altered cell cycle‐related gene expression in brain and lymphocytes from a transgenic mouse model of Alzheimer’s disease [amyloid precursor protein/presenilin 1 (PS1)]
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