Widespread distribution of orexin in rat brain and its regulation upon fasting.
Explore this paper's citation graph
Summary
The extensive and abundant distribution of orexins in the brain and changes in their contents upon fasting suggest that they serve as neuromodulators and/or neurotransmitters that regulate feeding behavior through interaction with diverse neural networks.
- Type
- article
- Published
- 1999-03-24
- Cited by
- 158
- References
- 9
- OpenAlex
- https://openalex.org/W2056656982
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:33372581
Keywords
Internal medicine, Hypothalamus, Orexin, Endocrinology, Pons
References
- Handbook of the hypothalamus
- Interconversion of methionine and methionine sulfoxide.
- Molecular forms of atrial natriuretic polypeptides in mammalian tissues and plasma.
- The melanin‐concentrating hormone system of the rat brain: An immuno‐ and hybridization histochemical characterization
- A role for melanin-concentrating hormone in the central regulation of feeding behaviour
- Hypocretin/Orexin‐ and melanin‐concentrating hormone‐expressing cells form distinct populations in the rodent lateral hypothalamus: Relationship to the neuropeptide Y and agouti gene‐related protein systems
- Circadian rhythm of adenosine-3',5'-monophosphate content in suprachiasmatic nucleus (SCN) and ventromedial hypothalamus (VMH) in the rat.
- Melanin-concentrating hormone acutely stimulates feeding, but chronic administration has no effect on body weight.
- Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior.
Cited by
- Linkage and physical mapping of the porcine prepro-orexin gene
- Expression of hypothalamic neuropeptides after acute TCDD treatment and distribution of Ah receptor repressor.
- Variants of the orexin2/hcrt2 receptor gene identified in patients with excessive daytime sleepiness and patients with Tourette's syndrome comorbidity
- Prepro-orexin mRNA expression in the rat brain is increased during pregnancy.
- Central orexin sensitivity, physical activity, and obesity in diet-induced obese and diet-resistant rats.
- Orphan G-Protein-Coupled Receptors
- Orexin and central regulation of cardiorespiratory system.
- The novel role of the neuropeptides orexin and QRFP and their involvement in Alzheimer's disease
- Rola wybranych czynników oreksygenicznych: oreksyny A (OXA), oreksyny B (OXB), greliny (GRE) i anoreksygenicznych: leptyny (LEP) w kontroli homeostazy organizmu w warunkach fizjologii
- Hypothalamic connections with the cerebral cortex.
- Neuropeptide Y Counteracts the Anorectic and Weight Reducing Effects of Ciliary Neurotropic Factor
- Effect of intestinal ischemia-reperfusion injury on protein levels of leptin and orexin-A in peripheral blood and central secretory tissues.
- Studies on OX1 Orexin Receptor Coupling to Arachidonic Acid and Endocannabinoid Signaling
- The hypothalamus and the control of energy homeostasis: different circuits, different purposes.
- Fasting Stimulates Tuberoinfundibular Dopaminergic Neuronal Activity and Inhibits Prolactin Secretion in Oestrogen‐Primed Ovariectomized Rats: Involvement of Orexin A and Neuropeptide Y
- Regulation of arcuate nucleus kisspeptin/neurokinin B and gonadotropin-releasing hormone during negative energy balance
- Neuropeptides controlling energy balance: orexins and neuromedins
- The hypocretin/orexin ligand-receptor system: implications for sleep and sleep disorders.
- Possible involvement of orexin in the stress reaction in rats.
- Changes in orexin-A and neuropeptide y expression in the hypothalamus of obese and lean Zucker Diabetic Fatty rats.
Related papers
- Neuropeptide Y mediates orexin A-mediated suppression of pulsatile gonadotropin-releasing hormone secretion in ovariectomized rats.
- A Major Role for Perifornical Orexin Neurons in the Control of Glucose Metabolism in Rats
- The Central Effects of Orexin‐A in the Hypothalamic‐Pituitary‐Adrenal Axis In Vivo and In Vitro in Male Rats
- Galanin‐Like Peptide Promotes Feeding Behaviour Via Activation of Orexinergic Neurones in the Rat Lateral Hypothalamus
- Characterization of orexins (hypocretins) and melanin-concentrating hormone in genetically obese mice.
- Differential Regulation of Leptin Receptor But Not Orexin in the Hypothalamus of the Lactating Rat
- The Role of Neuropeptide Y in Orexin‐Induced Hypothalamic‐Pituitary‐Adrenal Activation
- Association of expression of prepro-orexin and orexin receptors with hypothalamic-pituitary-adrenal axis in obese rats
- Orexin‐A Immunoreactivity and Prepro‐Orexin mRNA Expression in Hyperphagic Rats Induced By Hypothalamic Lesions and Lactation
- Orexins/hypocretins in the ob/ob mouse: hypothalamic gene expression, peptide content and metabolic effects.