The Central Effects of Orexin‐A in the Hypothalamic‐Pituitary‐Adrenal Axis In Vivo and In Vitro in Male Rats
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Summary
Results suggest that orexin‐A is involved in activation of the HPA axis, and that these effects could be mediated via the release of NPY.
- Type
- article
- Published
- 2001-06-01
- Cited by
- 134
- References
- 49
- OpenAlex
- https://openalex.org/W1792078704
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:32122851
Keywords
Internal medicine, Endocrinology, Orexin, Neuropeptide Y receptor, Vasopressin
References
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- The identification of a cis-acting element involved in cyclic 3',5'-adenosine monophosphate regulation of bovine vasopressin gene expression.
- A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains
- Neurons Containing Hypocretin (Orexin) Project to Multiple Neuronal Systems
- Isolation of clones of rat striatum-specific mRNAs by directional tag PCR subtraction
- Central Administration of Orexin A Suppresses Basal and Domperidone Stimulated Plasma Prolactin
- Possible involvement of orexin in the stress reaction in rats.
- Centrally administered orexin/hypocretin activates HPA axis in rats
- ACTH-induced excessive grooming in the rat.
- Neuropeptide Y potentiates luteinizing hormone (LH)-releasing hormone-induced LH secretion only under conditions leading to preovulatory LH surges.
- Structure and Function of Human Prepro-orexin Gene*
- Neuropeptide Y (NPY) in the area of the hypothalamic paraventricular nucleus activates the pituitary-adrenocortical axis in the rat.
- CRF-induced excessive grooming behavior in rats and mice.
- Radioimmunoassay of neuropeptide Y.
- Orexins, orexigenic hypothalamic peptides, interact with autonomic, neuroendocrine and neuroregulatory systems.
- Simultaneous determination of blood levels of corticosterone and growth hormone in the male rat: relation to sleep-wakefulness cycle.
- Glucagon-like peptide-1 stimulates luteinizing hormone-releasing hormone secretion in a rodent hypothalamic neuronal cell line.
- Steroid modulation of neuropeptide Y-induced luteinizing hormone releasing hormone release from median eminence fragments from male rats.
- Evidence that the central noradrenergic and adrenergic pathways activate the hypothalamic-pituitary-adrenal axis in the sheep.
Cited by
- Orexins and their receptors: structural aspects and role in peripheral tissues
- CSF-hypocretin-1 levels in patients with major depressive disorder compared to healthy controls.
- The role of orexin/hypocretin in the central nervous system and peripheral tissues.
- Orexin- A im Liquor cerebrospinalis bei Patienten mit uni- und bipolar affektiver Störung und gesunden Kontrollen
- Role of activatory and inhibitory neuropeptides in the regulation of the hypothalamo-pituitary-adrenal system
- OREXIN, STRESS AND ANXIETY/PANIC STATES
- Phospholipase Cascades in OX1 Orexin Receptor Signaling
- Understanding how discrete populations of hypothalamic neurons orchestrate complicated behavioral states
- Palatable Solutions During Paradoxical Sleep Deprivation: Reduction of Hypothalamic‐Pituitary‐Adrenal Axis Activity and Lack of Effect on Energy Imbalance
- The role of hypothalamic pathways in the metabolic side effects of Olanzapine
- Die Rolle der Hypocretine bei affektiven Störungen
- Hypothalamic Interactions Between Neuropeptide Y, Agouti‐Related Protein, Cocaine‐ and Amphetamine‐Regulated Transcript and Alpha‐Melanocyte‐Stimulating Hormone In Vitro in Male Rats
- Hypocretin-1 receptors regulate the reinforcing and reward-enhancing effects of cocaine: pharmacological and behavioral genetics evidence
- Effect of orexin infusion into third ventricle on the metabolic parameters in the goats fed low energy levels in diets.
- Antiallodynic Effects of Intrathecal Orexins in a Rat Model of Postoperative Pain
- Different neuronal phenotypes in the lateral hypothalamus and their role in sleep and wakefulness
- Blockade of orexin receptor 1 attenuates the development of morphine tolerance and physical dependence in rats.
- Cellular mechanisms of orexin actions on paraventricular nucleus neurones in rat hypothalamus
- Dual orexin receptor antagonists - promising agents in the treatment of sleep disorders.
- Chronic intraparaventricular nuclear administration of orexin A in male rats does not alter thyroid axis or uncoupling protein-1 in brown adipose tissue.
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