Lack of direct effect of moderate hyperleptinemia to improve endothelial function in lean rat aorta: role of calorie restriction.
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Summary
Moderate short-term calorie restriction with adaptive hypoleptinemia has independent beneficial effects on endothelial function in lean animals by enhancing eNOS expression and function and physiological hyperleaptinemia does not independently contribute to improved vascular function above and beyond the effect of calorie restriction.
- Type
- article
- Published
- 2004-08-01
- Cited by
- 27
- References
- 30
- OpenAlex
- https://openalex.org/W2056205710
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:27424567
Keywords
Leptin, Endocrinology, Internal medicine, Enos, Calorie restriction
References
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- Role of Sympathetic Activity in Blood Pressure Reduction With Low Calorie Regimen
- Regulation of endothelial constitutive nitric oxide synthase gene expression in endothelial cells and in vivo : a specific vascular action of insulin.
- Leptin induces direct vasodilation through distinct endothelial mechanisms.
Cited by
- Leptin-induced endothelial dysfunction in obesity.
- Age-related cardiovascular disease and the beneficial effects of calorie restriction
- Role of leptin in blood pressure regulation and arterial hypertension
- Short-term physiological hyperleptinemia decreases arterial blood pressure.
- Leptin and atherosclerosis.
- Phosphodiesterase 5 inhibitor ameliorates renal resistance to atrial natriuretic peptide associated with obesity and hyperleptinemia.
- VASODILATOR EFFECTS OF LEPTIN ON CANINE ISOLATED MESENTERIC ARTERIES AND VEINS
- Mild caloric restriction reduces blood pressure and activates endothelial AMPK-PI3K-Akt-eNOS pathway in obese Zucker rats.
- Effect of hyperleptinemia on endothelial nitric oxide production.
- A Positive Association between Leptin and Blood Pressure of Normal Range in Japanese Men
- Inflammation and insulin resistance in uremia.
- Calorie restriction protects against age‐related rat aorta sclerosis
- Caloric restriction increases internal iliac artery and penil nitric oxide synthase expression in rat: comparison of aged and adult rats.
- Endothelial effects of leptin: Implications in health and diseases
- Caloric restriction improves endothelial dysfunction during vascular aging: Effects on nitric oxide synthase isoforms and oxidative stress in rat aorta.
- Gender-specific effects of caloric restriction on the balance of vascular nitric oxide and superoxide radical.
- Calorie restriction and resveratrol in cardiovascular health and disease.
- Assessment of enhanced endothelium-dependent vasodilation by intermittent fasting in Wistar albino rats.
- The Effect of Short-Term and Subchronic Food Restriction on the Contractile Reactivity of Thoracic Aorta from Male Rats
- The importance of gastrointestinal hormones in the development of obesity-related hypertension
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