Expression of vascular endothelial growth factor‐A and mRNA stability factor HuR in human astrocytic tumors
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Summary
The findings suggest that the expression of VEGF‐A and cytoplasmic translocation of HuR relates to the histological grade, and that HuR is involved in the upregulation of VEL‐A expression, in human astrocytic tumors.
- Type
- article
- Published
- 2008-12-01
- Cited by
- 16
- References
- 21
- OpenAlex
- https://openalex.org/W2049642657
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:205471866
Keywords
Downregulation and upregulation, Vascular endothelial growth factor, Angiogenesis, Cancer research, Messenger RNA
References
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- Concentration of vascular endothelial growth factor in the serum and tumor tissue of brain tumor patients.
- Post-transcriptional regulation of vascular endothelial growth factor: implications for tumor angiogenesis.
- Overexpression of cyclooxygenase-2 correlates with cytoplasmic HuR expression in salivary mucoepidermoid carcinoma but not in pleomorphic adenoma.
- HuR: Post-Transcriptional Paths to Malignancy
- New horizons for VEGF. Is there a role for nuclear localization?
- Cytoplasmic HuR expression is a prognostic factor in invasive ductal breast carcinoma.
- Levels of vascular endothelial growth factor, hepatocyte growth factor/scatter factor and basic fibroblast growth factor in human gliomas and their relation to angiogenesis
- Post-transcriptional Regulation of Vascular Endothelial Growth Factor by Hypoxia (*)
- Prognostic significance of microvessel density determined by an anti‐CD105/endoglin monoclonal antibody in astrocytic tumors: Comparison with an anti‐CD31 monoclonal antibody
- Overexpression of the Embryonic-Lethal Abnormal Vision-like Protein HuR in Ovarian Carcinoma Is a Prognostic Factor and Is Associated with Increased Cyclooxygenase 2 Expression
- Expression of vascular endothelial growth factor-A and mRNA stability factor HuR in human meningiomas
- The classification of tumours of the central nervous system.
- Cyclooxygenase-2 Is an Independent Prognostic Factor in Gastric Cancer and Its Expression Is Regulated by the Messenger RNA Stability Factor HuR
- Angiogenesis in Gliomas: Biology and Molecular Pathophysiology
- Levels of soluble vascular endothelial growth factor (VEGF) receptor 1 in astrocytic tumors and its relation to malignancy, vascularity, and VEGF-A.
- Cytoplasmic HuR expression correlates with poor outcome and with cyclooxygenase 2 expression in serous ovarian carcinoma.
- Macrophage infiltration-associated thymidine phosphorylase expression correlates with increased microvessel density and poor prognosis in astrocytic tumors.
- Tumor necrosis factor alpha induces angiogenic factor up-regulation in malignant glioma cells: a role for RNA stabilization and HuR.
- HuR, a RNA stability factor, is expressed in malignant brain tumors and binds to adenine- and uridine-rich elements within the 3' untranslated regions of cytokine and angiogenic factor mRNAs.
Cited by
- The role of YKL-40 in the progression of glioblastoma
- 3′UTR elements inhibit Ras‐induced C/EBPβ post‐translational activation and senescence in tumour cells
- Clinical significance of HuR expression in human malignancy
- Intestinal epithelial HuR modulates distinct pathways of proliferation and apoptosis and attenuates small intestinal and colonic tumor development
- The role of mammalian ribonucleases (RNases) in cancer.
- Role of YKL-40 in the Angiogenesis, Radioresistance, and Progression of Glioblastoma*
- Vascular endothelial growth factor expression and angiogenesis in various grades and subtypes of meningioma.
- Oncogenesis recapitulates embryogenesis via the hypoxia pathway: morphoproteomics and biomedical analytics provide proof of concept and therapeutic options.
- Xiaotan Sanjie decoction inhibits angiogenesis in gastric cancer through Interleukin-8-linked regulation of the vascular endothelial growth factor pathway.
- Leptomycin B ameliorates vasogenic edema formation induced by status epilepticus via inhibiting p38 MAPK/VEGF pathway.
- Long non-coding RNA SNHG12promotes the proliferation and migration of glioma cells by binding to HuR.
- Protein-protein interactions reveal key canonical pathways, upstream regulators, interactome domains, and novel targets in ALS
- The Diverse Roles of RNA-Binding Proteins in Glioma Development.
- Characterizing the endoribonuclease activity of APE1.
- Hu Antigen R (HuR) Protein Structure, Function and Regulation in Hepatobiliary Tumors
- The Role of Tumor-Intrinsic HuR in Modeling the Pancreatic Tumor Microenvironment: Molecular Mechanisms and Therapeutic Opportunities
- HuR-induced CDK2 translational enhancement aggravates oral tongue squamous carcinoma
- Role of bevacizumab therapy in the management of glioblastoma
- HuR-induced CDK2 translational enhancement aggravates oral tongue squamous carcinoma
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