Availability of activated CD4+ T cells dictates the level of viremia in naturally SIV-infected sooty mangabeys.

Keywords

Viremia, Biology, CD14, Virology, Viral replication

References

• Viral dynamics in human immunodeficiency virus type 1 infectionLydia Feito Grande, Alicia Villar Ezcurra — 1995
• Recovery of immune reactivity after T-cell-depleted bone marrow transplantation depends on thymic activity.Étienne Roux, Florence Dumont-Girard, Michel Starobinski — 2000
• The Influence of Age on T Cell Generation and TCR Diversity1Keith Naylor, Guangjin Li, Abbe N. Vallejo — 2005
• Correlates of Preserved CD4+ T Cell Homeostasis during Natural, Nonpathogenic Simian Immunodeficiency Virus Infection of Sooty Mangabeys: Implications for AIDS PathogenesisBeth Sumpter, Richard M. Dunham, Shari N. Gordon — 2007
• Depletion of CD8+ Cells in Sooty Mangabey Monkeys Naturally Infected with Simian Immunodeficiency Virus Reveals Limited Role for Immune Control of Virus Replication in a Natural Host Species1Ashley P. Barry, Guido Silvestri, Jeffrey T. Safrit — 2007
• Immunopathogenic Mechanisms of HIV InfectionZeda Rosenberg, Anthony S. Fauci — 1996
• Pathogenesis of AIDS: the non-human primate model.Philip R. Johnson, Vanessa M. Hirsch — 1991
• Recovery of Lymphocyte and Dendritic Cell Subsets Following Reduced Intensity Allogeneic Bone Marrow TransplantationMohamad Mohty, Béatrice Gaugler, Catherine Faucher — 2002
• HCV Persistence and Immune Evasion in the Absence of Memory T Cell HelpArash Grakoui, Naglaa H. Shoukry, David J. Woollard — 2003
• CD4+ T-cell depletion in HIV infection: Are we closer to understanding the cause?Zvi Grossman, Martin Meier‐Schellersheim, Ana E. Sousa — 2002
• The dynamics of CD4+ T-cell depletion in HIV diseaseJoseph M. McCune — 2001
• Peak SIV replication in resting memory CD4+ T cells depletes gut lamina propria CD4+ T cellsQingsheng Li, Lijie Duan, Jacob D. Estes — 2005
• Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infectionDavid D. Ho, Avidan U. Neumann, Alan S. Perelson — 1995
• HIV-1 pathogenesisMario Stevenson — 2003
• Human infection by genetically diverse SIVSM-related HIV-2 in West AfricaFeng Gao, Ling Yue, A T White — 1992
• HIV-1 Dynamics in Vivo: Virion Clearance Rate, Infected Cell Life-Span, and Viral Generation TimeAlan S. Perelson, Avidan U. Neumann, Martin Markowitz — 1996
• Nonpathogenic SIV infection of sooty mangabeys is characterized by limited bystander immunopathology despite chronic high-level viremia.Guido Silvestri, Donald L. Sodora, Richard A. Koup — 2003
• Effect of CD8+ Lymphocyte Depletion on Virus Containment after Simian Immunodeficiency Virus SIVmac251 Challenge of Live Attenuated SIVmac239Δ3-Vaccinated Rhesus MacaquesJörn E. Schmitz, R. Paul Johnson, Harold M. McClure — 2005
• Turnover of lymphocytes and conceptual paradigms in HIV infection.Guido Silvestri, Mark B. Feinberg — 2003
• Viral dynamics in HIV-1 infection.Diana Finzi, Robert F. Siliciano — 1998

Cited by

• Incorporation of innate immune effector mechanisms in the formulation of a vaccine against HIV-1.Aftab A. Ansari, Ann E. Mayne, Yoshiaki Takahashi — 2011
• Subtle Mimicry of HLA by HIV-1 GP120 – A Role for Anti HLA Antibodies?Peter L. Smith, Angus Dalgleish — 2010
• Preliminary in vivo efficacy studies of a recombinant rhesus anti-α4β7 monoclonal antibodyLara Pereira, Nattawat Onlamoon, X. Wang — 2009
• Cutting Edge: Experimentally Induced Immune Activation in Natural Hosts of Simian Immunodeficiency Virus Induces Significant Increases in Viral Replication and CD4+ T Cell Depletion1Ivona Pandrea, Thaidra Gaufin, Jason M. Brenchley — 2008
• Mechanisms of down-regulation of immune activation and B-cell responses in the natural hosts of simian immunodeficiency virusJanna Seifried — 2012
• Reduced Simian Immunodeficiency Virus Replication in Macrophages of Sooty Mangabeys Is Associated with Increased Expression of Host Restriction FactorsKiran D. Mir, Maud Mavigner, Charlene Wang — 2015
• Compromised gastrointestinal integrity in pigtail macaques is associated with increased microbial translocation, immune activation and IL-17 production in the absence of SIV infectionN R Klatt, L. D. Harris, Carol L. Vinton — 2010
• Target Cell Availability, Rather than Breast Milk Factors, Dictates Mother-to-Infant Transmission of SIV in Sooty Mangabeys and Rhesus MacaquesAnn Chahroudi, Emily K. Cartwright, S. Thera Lee — 2014
• Immunopathogenesis of Simian Immunodeficiency Virus (SIV) Infection in Nonhuman PrimatesJörn E. Schmitz, Birgit Korioth-Schmitz — 2013
• Toward an AIDS vaccine: lessons from natural simian immunodeficiency virus infections of African nonhuman primate hostsDonald L. Sodora, Jonathan S. Allan, Cristian Apetrei — 2009
• Where the Wild Things Are: Pathogenesis of SIV Infection in African Nonhuman Primate HostsIvona Pandrea, Cristian Apetrei — 2010
• Down-regulation of CD4 by memory CD4+ T cells in vivo renders African green monkeys resistant to progressive SIVagm infectionCoreen M. Beaumier, Levelle D. Harris, Simoy Goldstein — 2009
• Infection, Viral Dissemination, and Antibody Responses of Rhesus Macaques Exposed to the Human Gammaretrovirus XMRVNattawat Onlamoon, Jaydip Das Gupta, Prachi Sharma — 2011
• Bone marrow-based homeostatic proliferation of mature T cells in nonhuman primates: implications for AIDS pathogenesis.Mirko Paiardini, Barbara Cervasi, Jessica C. Engram — 2009
• Increased Stability and Limited Proliferation of CD4+ Central Memory T Cells Differentiate Nonprogressive Simian Immunodeficiency Virus (SIV) Infection of Sooty Mangabeys from Progressive SIV Infection of Rhesus MacaquesColleen S. McGary, Barbara Cervasi, Ann Chahroudi — 2014
• SIV infection in natural hosts: Resolution of immune activation during the acute-to-chronic transition phaseKiran D. Mir, Melanie Gasper, Vasudha Sundaravaradan — 2010
• Immunodeficiency lentiviral infections in natural and non-natural hosts.Jason M. Brenchley, Mirko Paiardini — 2011
• Th17 Cell Dynamics in HIV InfectionNichole R. Klatt, Jason M. Brenchley — 2010
• The Cytokine Network of Acute HIV Infection: A Promising Target for Vaccines and Therapy to Reduce Viral Set-Point?Peter D. Katsikis, Yvonne M. Mueller, François Villinger — 2011
• Immunology and the elusive AIDS vaccineHerbert W. Virgin, Bruce D. Walker — 2010

Related papers

• Wide Range of Viral Load in Healthy African Green Monkeys Naturally Infected with Simian Immunodeficiency VirusSimoy Goldstein, Ilnour Ourmanov, Charles R. Brown — 2000
• CD8+-Cell-Mediated Suppression of Virulent Simian Immunodeficiency Virus during Tenofovir TreatmentKoen K. A. Van Rompay, Raman P. Singh, Bapi Pahar — 2004
• Control of viremia in simian immunodeficiency virus infection by CD8+ lymphocytes.Jörn E. Schmitz, Marcelo J. Kuroda, Sampa Santra — 1999
• Protection against Mucosal Simian Immunodeficiency Virus SIVmac251 Challenge by Using Replicating Adenovirus-SIV Multigene Vaccine Priming and Subunit BoostingL. Jean Patterson, Nina Malkevitch, David Venzon — 2004
• Establishment of Monkey Model with Chronic Infection of Simian Acquired Immunodeficiency VirusWu Xiaoxian — 2000
• Viral load assay sensitivity and low level viremia in HAART treated HIV patients.Chris Verhofstede, Filip Van Wanzeele, Jacqueline Reynaerts — 2010
• Transient Viremia, Plasma Viral Load, and Reservoir Replenishment in HIV-Infected Patients on Antiretroviral TherapyLaura Jones, Alan S. Perelson — 2007
• A Period of Transient Viremia and Occult Infection Precedes Persistent Viremia and Antiviral Immune Responses during Multiple Low-Dose Intravaginal Simian Immunodeficiency Virus InoculationsZhong-Min Ma, Kristina Abel, Tracy Rourke — 2004
• Passive infusion of immune serum into simian immunodeficiency virus-infected rhesus macaques undergoing a rapid disease course has minimal effect on plasma viremia.James Μ. Binley, Brian Clas, Agegnehu Gettie — 2000
• What can natural infection of African monkeys with simian immunodeficiency virus tell us about the pathogenesis of AIDS?Vanessa M. Hirsch — 2004