Little Evidence for Developmental Plasticity of Adult Hematopoietic Stem Cells
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Summary
The data indicate that “transdifferentiation” of circulating HSCs and/or their progeny is an extremely rare event, if it occurs at all.
- Type
- article
- Published
- 2002-09-05
- Cited by
- 1,529
- References
- 32
- OpenAlex
- https://openalex.org/W2048258494
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:43452175
Keywords
Transdifferentiation, Haematopoiesis, Green fluorescent protein, Biology, Stem cell
References
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- Bone marrow as a potential source of hepatic oval cells.
- Muscle regeneration by bone marrow-derived myogenic progenitors.
- Bone marrow cells adopt the phenotype of other cells by spontaneous cell fusion
- Intestinal crypt survival and total and per crypt levels of proliferative cellularity following irradiation: fractionated x-ray exposures.
- The long-term repopulating subset of hematopoietic stem cells is deterministic and isolatable by phenotype.
- Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell.
- Binucleation and polyploidization patterns in developmental and regenerative rat liver growth
- Cyclophosphamide/granulocyte colony-stimulating factor causes selective mobilization of bone marrow hematopoietic stem cells into the blood after M phase of the cell cycle.
- Physiological Migration of Hematopoietic Stem and Progenitor Cells
- Recovery of function and cell population in the intestinal epithelium of x-irradiated mice.
- Transplanted Adult Bone Marrow Cells Repair Myocardial Infarcts in Mice
- Xenogeneic Monoclonal Antibodies to Mouse Lymphoid Differentiation Antigens *
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- Bone marrow: an extra-pancreatic hideout for the elusive pancreatic stem cell?
- Therapeutic stem and progenitor cell transplantation for organ vascularization and regeneration
- Participation of Bone Marrow-Derived Cells in Long-Term Repair Processes after Experimental Stroke
- Significant differences among skeletal muscles in the incorporation of bone marrow-derived cells.
- Lung cells transplanted to irradiated recipients generate lymphohematopoietic progeny.
- Some like it plastic.
- Stem Cell Plasticity in the Hematopoietic System
- Stem cell origin of cancer and differentiation therapy.
- Formation of human hepatocytes by human hematopoietic stem cells in sheep.
- Identification of hematopoietic stem/progenitor cells: strength and drawbacks of functional assays
- The engraftment of transplanted bone marrow-derived cells into the olfactory epithelium.
- Thermoreversible gelation polymer induces the emergence of hepatic stem cells in the partially injured rat liver
- Adult stem cell plasticity
- Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma
- Hematopoietic Stem Cells Derived From Adult Donors Are Not a Source of Pancreatic β-Cells in Adult Nondiabetic Humans
- Are postnatal hemangioblasts generated by dedifferentiation from committed hematopoietic stem cells?
- Engineering vascularised tissues in vitro.
- Functional Overloading of Dystrophic Mice Enhances Muscle-Derived Stem Cell Contribution to Muscle Contractile Capacity
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