Multiple nuclear localization signals in XPG nuclease.
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Summary
Evidence is reported for the mechanism of nuclear localization of XPG nuclease in human cells using in situ immunofluorescene localization of transiently expressed beta-galactosidase fusion proteins and for the peptides containing functional NLS.
- Type
- article
- Published
- 1996-05-15
- Cited by
- 29
- References
- 34
- OpenAlex
- https://openalex.org/W2048130209
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:7113403
Keywords
NLS, Nuclear localization sequence, Nuclease, Biology, Cell biology
References
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- Isolation of a human lymphoblastoid line heterozygous at the thymidine kinase locus: possibility for a rapid human cell mutation assay.
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- Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase.
- Nuclear protein migration involves two steps: rapid binding at the nuclear envelope followed by slower translocation through nuclear pores.
- XPG endonuclease makes the 3′ incision in human DNA nucleotide excision repair
Cited by
- XPG: its products and biological roles.
- Regulation of base excision repair in eukaryotes by dynamic localization strategies.
- Cytomegalovirus Assembly Protein Precursor and Proteinase Precursor Contain Two Nuclear Localization Signals That Mediate Their Own Nuclear Translocation and That of the Major Capsid Protein
- Cellular stress responses in equine tendon fibroblast monolayers
- Nuclear localization of the Epstein-Barr virus EBNA3B protein.
- Identification of Two Novel Nuclear Import Sequences on the 5-Lipoxygenase Protein*
- Epstein-Barr virus DNase contains two nuclear localization signals, which are different in sensitivity to the hydrophobic regions.
- Nuclear translocation contributes to regulation of DNA excision repair activities.
- The puzzle of PCNA's many partners
- Relationship of neurologic degeneration to genotype in three xeroderma pigmentosum group G patients.
- ERCC5 (xeroderma pigmentosum, complementation group G)
- Molecular cloning and structural analysis of the functional mouse genomic XPG gene
- Cell Cycle-dependent and DNA Damage-inducible Nuclear Localization of FEN-1 Nuclease Is Consistent with Its Dual Functions in DNA Replication and Repair*
- The XPG story.
- The DNA Repair Endonuclease XPG Binds to Proliferating Cell Nuclear Antigen (PCNA) and Shares Sequence Elements with the PCNA-binding Regions of FEN-1 and Cyclin-dependent Kinase Inhibitor p21*
- Newly Discovered Archaebacterial Flap Endonucleases Show a Structure-Specific Mechanism for DNA Substrate Binding and Catalysis Resembling Human Flap Endonuclease-1*
- Identification of Nuclear Import and Export Signals within Fli-1: Roles of the Nuclear Import Signals in Fli-1-Dependent Activation of Megakaryocyte-Specific Promoters
- Bioinformatic analysis of the nucleolus.
- Regulation of nucleocytoplasmic localization of the atDjC6 chaperone protein
- Cross-talk between nucleotide excision and homologous recombination DNA repair pathways in the mechanism of action of antitumor trabectedin.
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