Application of gene expression profiling to cardiovascular disease.
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Summary
Four profiling techniques; serial analysis of gene expression, differential display, subtractive hybridisation and DNA microarrays are introduced and their potential for gene discovery and improving the understanding of gene function is discussed.
- Type
- review
- Published
- 2002-04-01
- Cited by
- 43
- References
- 61
- Access
- Open access
- OpenAlex
- https://openalex.org/W2045929470
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:43283920
Keywords
DNA microarray, Gene expression profiling, Gene expression, Serial analysis of gene expression, Computational biology
References
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- Perspectives for vascular genomics
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- Quantitative Monitoring of Gene Expression Patterns with a Complementary DNA Microarray
- Gene program for cardiac cell survival induced by transient ischemia in conscious pigs
- High-level expression of Egr-1 and Egr-1-inducible genes in mouse and human atherosclerosis.
- Identifying changes in gene expression in the nervous system: mRNA differential display.
- Cloning the differences between two complex genomes
- Overexpression of Eotaxin and the CCR3 Receptor in Human Atherosclerosis: Using Genomic Technology to Identify a Potential Novel Pathway of Vascular Inflammation
- Suppression subtractive hybridization: a method for generating differentially regulated or tissue-specific cDNA probes and libraries.
- The Tangier disease gene product ABC1 controls the cellular apolipoprotein-mediated lipid removal pathway.
- Quantitative assessment of DNA microarrays--comparison with Northern blot analyses.
- Overcoming limitations of the mRNA differential display technique.
- Gene expression profiling of cardiovascular disease models.
- Expression profiling reveals distinct sets of genes altered during induction and regression of cardiac hypertrophy.
- Identification of vascular endothelial genes differentially responsive to fluid mechanical stimuli: cyclooxygenase-2, manganese superoxide dismutase, and endothelial cell nitric oxide synthase are selectively up-regulated by steady laminar shear stress.
- Use of serial analysis of gene expression (SAGE) technology.
- Importance of replication in microarray gene expression studies: statistical methods and evidence from repetitive cDNA hybridizations.
Cited by
- Transcriptional profiling of early onset diet-induced atherosclerosis in apolipoprotein E-deficient mice.
- Transcriptome Analysis Describing New Immunity and Defense Genes in Peripheral Blood Mononuclear Cells of Rheumatoid Arthritis Patients
- Integration of genomics, proteomics, and imaging for cardiac stem cell therapy
- Peripheral blood mononuclear cells (PBMCs): a possible model for studying cardiovascular biology systems
- Phenylephrine and endothelin-1 upregulate connective tissue growth factor in neonatal rat cardiac myocytes.
- Regulation of gene and protein expression in cardiac myocyte hypertrophy and apoptosis.
- Differential gene expression in skeletal muscle after induction of heart failure: impact of cytokines on protein phosphatase 2A expression.
- What is the relevance of bioinformatics to pharmacology?
- Effects of A1 adenosine receptor overexpression on normoxic and post-ischemic gene expression.
- A unified computational model for revealing and predicting subtle subtypes of cancers
- Transcriptional profiling of in vitro smooth muscle cell differentiation identifies specific patterns of gene and pathway activation.
- Genomic profiling of left and right ventricular hypertrophy in congenital heart disease.
- Computational physiology and the physiome project
- Gene expression profiling in hypertension research: a critical perspective.
- Transcriptional profiling of reporter genes used for molecular imaging of embryonic stem cell transplantation.
- Microarray Profiling of Lymphocytes in Internal Diseases With an Altered Immune Response: Potential and Methodology
- Uncomplicated human obesity is associated with a specific cardiac transcriptome: involvement of the Wnt pathway
- The role of endomyocardial biopsy in the management of cardiovascular disease: a scientific statement from the American Heart Association, the American College of Cardiology, and the European Society of Cardiology.
- Transcriptional profiling and network analysis of the murine angiotensin II-induced abdominal aortic aneurysm.
- Analysis of gene expression during the macrophage to foam cell transformation using cDNA arrays
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