The BRCA1/BARD1 Heterodimer Assembles Polyubiquitin Chains through an Unconventional Linkage Involving Lysine Residue K6 of Ubiquitin*

Keywords

Ubiquitin, Ubiquitin ligase, Lysine, Chemistry, Biochemistry

References

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• The RING Heterodimer BRCA1-BARD1 Is a Ubiquitin Ligase Inactivated by a Breast Cancer-derived Mutation*Rintaro Hashizume, Mamoru Fukuda, Ichiro Maeda — 2001

Cited by

• The ubiquitin-proteasome pathway and its role in cancer.浩己 藤田, 照和 西嵜, 昌孝 前田 — 2005
• Structural aspects of multi-domain RING/Ubox E3 ligases in DNA repair.R. P. S. Verma, Biplab Sarkar — 2009
• The ubiquitin proteasome system in neurodegenerative diseases: culprit, accomplice or victim?明弘 森, 義信 林, 文雄 川尻 — 2012
• The RING Finger Protein RNF8 Ubiquitinates Nbs1 to Promote DNA Double-strand Break Repair by Homologous Recombination*Chi-Sheng Lu, Lan N. Truong, Aaron Aslanian — 2012
• Analyse de l'expression de BARD1 dans le cancer du poumon et le cancer colorectalYong Zhang — 2010
• Studies on RNF8, a ubiquitin ligase with a RING finger domainVanessa Plans Calafell — 2005
• Defining the regulation and function of SAFB1 and SAFB2 in human breast cancer cellsElaine Hong — 2013
• Manipulation of the ubiquitin-proteasome system by HIV-1 : role of the accessory protein VprJean-Philippe Belzile — 2010
• Signalling functions of polyubiquitin chains and ubiquitin-binding domainsS. Zhao — 2010
• Etude de l'effet antitumoral de l'activation de la NO-synthase inductible dans un modèle de cancer du sein : analyse des mécanismes moléculairesM. Lamrani — 2013
• The Role of BRCA1 in DNA Double-strand Break RepairSeth M. Dever — 2009
• Characterisation of deubiquitinase enzymes involved in androgen receptor regulation in prostate cancerH. Ramsey — 2012
• ATM, BRCA1, and Aurora A: Mechanisms of G2/M Checkpoint Control in Human Embryonic Stem CellsJ. Beckta — 2014
• Characterization of the Ubc13-Mms2 Lysine-63-linked ubiquitin conjugating complexLandon Pastushok — 2006
• Implications of BRCA1 mutations in basal-like breast cancer development and treatmentYuexi Gu — 2015
• Chemical and genetic strategies for manipulating polyubiquitin chain structure.Sara Volk, Min Wang, Cecile M. Pickart — 2005
• Controlled synthesis of polyubiquitin chains.Cecile M. Pickart, Shahri Raasi — 2005
• DNA repair by HDR in experimental tumorigenesisUlrica Westermark — 2008
• Accumulation of polyubiquitinated proteins by overexpression of RBCC protein interacting with protein kinase C2, a splice variant of ubiquitin ligase RBCC protein interacting with protein kinase C1Nobuo Yoshimoto, Kenji Tatematsu, Toshihide Okajima — 2009
• Regulation of Estrogen Receptor alpha Ubiquitination and Proteasome-mediated Receptor DegradationNicholas B Berry — 2008

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