The effect of KIR ligand incompatibility on the outcome of unrelated donor transplantation: a report from the center for international blood and marrow transplant research, the European blood and marrow transplant registry, and the Dutch registry.
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Summary
Patients who received grafts from donors mismatching at the KIR ligand in the GVH or HVG direction and mismatched at HLA-B and/or C but matched at the kir ligand had similar rates of TRM, treatment failure, and overall mortality.
- Type
- article
- Published
- 2006-08-01
- Cited by
- 254
- References
- 37
- Access
- Open access
- OpenAlex
- https://openalex.org/W16864058
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:9178513
Keywords
Computer science, Philosophy
References
- Impact of HLA class I and class II high-resolution matching on outcomes of unrelated donor bone marrow transplantation: HLA-C mismatching is associated with a strong adverse effect on transplantation outcome.
- Role of natural killer cell alloreactivity in HLA-mismatched hematopoietic stem cell transplantation.
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- Determinants of Antileukemia Effects of Allogeneic NK Cells 1
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- Results of allogeneic bone marrow transplants for leukemia using donors other than HLA-identical siblings.
- The beneficial role of inhibitory KIR genes of HLA class I NK epitopes in haploidentically mismatched stem cell allografts may be masked by residual donor-alloreactive T cells causing GVHD.
- Estimation of failure probabilities in the presence of competing risks: new representations of old estimators.
- Proposals for the classification of the myelodysplastic syndromes
- Alloreactive killer cells: hindrance and help for haematopoietic transplants
- Evaluation of KIR ligand incompatibility in mismatched unrelated donor hematopoietic transplants. Killer immunoglobulin-like receptor.
- Unrelated donor marrow transplantation for chronic myelogenous leukaemia
- Increased Infection-Related Mortality in KIR-Ligand–Mismatched Unrelated Allogeneic Hematopoietic Stem-Cell Transplantation
- Natural killer cell receptors: new biology and insights into the graft-versus-leukemia effect.
- KIR reconstitution is altered by T cells in the graft and correlates with clinical outcomes after unrelated donor transplantation.
- Relevance of KIR gene polymorphisms in bone marrow transplantation outcome.
- Genotypic inhibitory killer immunoglobulin-like receptor ligand incompatibility enhances the long-term antileukemic effect of unmodified allogeneic hematopoietic stem cell transplantation in patients with myeloid leukemias.
- The impact of donor KIR and patient HLA-C genotypes on outcome following HLA-identical sibling hematopoietic stem cell transplantation for myeloid leukemia.
- The repertoire of HLA–Cw‐specific NK cell receptors CD158 a/b (EB6 and GL183) in individuals with different HLA phenotypes
- T‐cell alloreactivity dominates natural killer cell alloreactivity in minimally T‐cell‐depleted HLA‐non‐identical paediatric bone marrow transplantation
Cited by
- GVHD pathophysiology: is acute different from chronic?
- Engineering antigen-specific primary human NK cells against HER-2 positive carcinomas
- The role of natural killer cells in cancer therapy.
- Natural killer cells and tumor control
- Clinical production and therapeutic applications of alloreactive natural killer cells.
- Risk-associations between HLA-DPB1 T cell epitope matching and outcome of unrelated hematopoietic cell transplantation are independent from HLA-DPA1
- The Impact of HLA and KIR Ligand Mismatching on Unrelated Allogeneic Hematopoietic Stem Cell Transplantation in Korean Adult Patients
- Greffes allogéniques à partir de donneurs non apparentés
- Greffes allogniques partir de donneurs non apparents
- Study of the activation of peripheral blood and cord blood natural killer cells
- Killer cell Immunoglobulin-like Receptor (KIR) polymorphism in Haematopoietic Stem Cell Transplantation (HSCT) : The effect of KIR gene and genotype polymorphism on clinical outcome after HSCT
- Immunotherapy in acute myeloid leukemia
- Impact of natural killer cell dose and donor killer‐cell immunoglobulin‐like receptor (KIR) genotype on outcome following human leucocyte antigen‐identical haematopoietic stem cell transplantation
- Intercellular protein transfer and regulation of inhibitory NK receptor accessibility
- Natural Killer Cells and the Immune Response in Solid Organ Transplantation
- The functional role of the activating receptors Tim-3 and CD16 in human natural killer (NK) cell biology
- Use of NK cell activity in cure by transplant
- 自然杀伤细胞与癌症——杀伤细胞免疫球蛋白样受体(KIR)的调控
- Autologous Stem Cell Transplant Recipients Tolerate Haploidentical Related-Donor Natural Killer Cell Enriched Infusions
- Inhibitory killer cell immunoglobulin‐like receptor (iKIR) mismatches improve survival after T‐cell‐repleted haploidentical transplantation
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