Preliminary evidence that Ghrelin, the natural GH secretagogue (GHS)-receptor ligand, strongly stimulates GH secretion in humans
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Summary
An endogenous ligand for the GH secretagogue-receptor (GHS-R) has been recently purified from rat and human stomach and named Ghrelin exerted a strong stimulatory effect on GH secretion in humans releasing more GH than GHRH.
- Type
- article
- Published
- 2000-09-01
- Cited by
- 410
- References
- 8
- OpenAlex
- https://openalex.org/W2040304426
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:40560740
Keywords
Ghrelin, Secretagogue, Endocrinology, Internal medicine, Growth hormone secretagogue receptor
References
- Ghrelin is a growth-hormone-releasing acylated peptide from stomach
- Growth hormone-releasing activity of hexarelin, a new synthetic hexapeptide, after intravenous, subcutaneous, intranasal, and oral administration in man.
- Dose-response relationships for the effects of growth hormone-releasing factor-(1-44)-NH2 in young adult men and women.
- Synthetic peptides and their non-peptidyl mimetics in endocrinology: From synthesis to clinical perspectives
- Ghrelin: a step forward in the understanding of somatotroph cell function and growth regulation.
- Peptidomimetic regulation of growth hormone secretion.
- Growth hormone-releasing peptides and the cardiovascular system.
- Chapter 12 – Hormonal Activities of Growth Hormone Secretagogues (GHS) across Human Lifespan
Cited by
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- Human Ghrelin Ameliorates Organ Injury and Improves Survival after Radiation Injury Combined with Severe Sepsis
- Ghrelin as a Novel Therapy for Radiation Combined Injury
- Assessment of Immune Cells Number and Function, Haemorheology and Gene Expression Following Short-term Administration of Recombinant Human Growth Hormone to Healthy Males
- Investigating the role of melanocortin system in regulating linear growth and growth hormone secretion
- Análisis de la actividad eléctrica espontánea en células somatotropas de origen bovino tratadas con GHRELINA
- The roles of the preproghrelin-derived peptides - ghrelin, desacyl ghrelin and obestatin - in prostate cancer
- Exercise-induced effects on growth hormone levels are associated with ghrelin changes only in presence of prolonged exercise bouts in male athletes.
- Implication de ghreline/obestatine, deux peptides issus du même précurseur, dans le contrôle de la sécrétion d'hormone de croissance et du comportement alimentaire.
- The structure and function of the human ghrelin receptor
- The effects of sleep dysregulation and adiponectin on immunity in older adults
- Changes in plasma ghrelin and growth hormone concentrations in mature Holstein cows and three-month-old calves.
- Relationship between body composition, growth hormone and ghrelin secretion in morbidly obese subjects before and after surgically induced weight loss
- Effect of sleep deprivation on exercise-induced growth hormone release
- Lipocalin-2 plasmatic levels are reduced in patients with long-term type 2 diabetes mellitus.
- Ghrelin is multifaceted hormone
- Ghrelin: A GH-Releasing, Appetite-Regulating Gastric Hormone
- Ghrelin Concentrations in Milk and Plasma of Dairy During Early Lactation
- EFFECTS OF WEIGHT LOSS ON VISCERAL ADIPOSITY AND METABOLIC ADAPTATIONS IN DIABETIC VERSUS NON-DIABETIC WOMEN
- Natural and Synthetic Growth Hormone Secretagogues
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