Human Ghrelin Ameliorates Organ Injury and Improves Survival after Radiation Injury Combined with Severe Sepsis
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Summary
The results showed that serum levels of ghrelin and its gene expression in the stomach were decreased markedly at 20 h after RCI, and the protective effect of human gh Relin appears to be attributed to rebalancing the dysregulated sympathetic/parasympathetic nervous systems.
- Type
- book
- Published
- 2009-09-18
- Cited by
- 53
- References
- 58
- Access
- Open access
- OpenAlex
- https://openalex.org/W19779631
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:16468663
Keywords
Futures contract, Currency, Liberian dollar, Hedge, Economics
References
- Ghrelin is a growth-hormone-releasing acylated peptide from stomach
- The effect of whole-body radiation on blood levels of gastrointestinal peptides in the rat.
- Increased serum levels of tumor necrosis factor alpha precede major complications of bone marrow transplantation.
- Novel connections between the neuroendocrine and immune systems: the ghrelin immunoregulatory network.
- Growth hormone secretagogue receptor expression in the cells of the stomach-projected afferent nerve in the rat nodose ganglion.
- Seasonal variation in the epidemiology of sepsis*
- Ghrelin--satisfying a hunger for the mechanism.
- The role of Kupffer cell alpha(2)-adrenoceptors in norepinephrine-induced TNF-alpha production.
- The epidemiology of sepsis.
- Ghrelin improves tissue perfusion in severe sepsis via downregulation of endothelin-1.
- Orexigenic Hormone Ghrelin Attenuates Local and Remote Organ Injury after Intestinal Ischemia-Reperfusion
- The pathophysiology and treatment of sepsis.
- Structure-function studies on the new growth hormone-releasing peptide, ghrelin: minimal sequence of ghrelin necessary for activation of growth hormone secretagogue receptor 1a.
- Pathophysiology of sepsis.
- Ghrelin attenuates sepsis-induced acute lung injury and mortality in rats.
- Physiology and immunology of the cholinergic antiinflammatory pathway.
- Ghrelin Down-regulates Proinflammatory Cytokines in Sepsis Through Activation of the Vagus Nerve
- Centrally administered ghrelin suppresses sympathetic nerve activity in brown adipose tissue of rats.
- Dose dependent effects of ghrelin on pentylenetetrazole-induced oxidative stress in a rat seizure model.
- Ghrelin--not just another stomach hormone.
Cited by
- Ghrelin Therapy Improves Survival after Whole-Body Ionizing Irradiation or Combined with Burn or Wound: Amelioration of Leukocytopenia, Thrombocytopenia, Splenomegaly, and Bone Marrow Injury
- Ghrelin therapy mitigates bone marrow injury and splenocytopenia by sustaining circulating G-CSF and KC increases after irradiation combined with wound
- Ghrelin as a Novel Therapy for Radiation Combined Injury
- Radiation Combined Injury: DNA Damage, Apoptosis, and Autophagy
- Human Ghrelin Protects Animals from Renal Ischemia-Reperfusion Injury through the Vagus Nerve
- Ghrelin and cachexia: Will treatment with GHSR-1a agonists make a difference for patients suffering from chronic wasting syndromes?
- Bilirubin augments radiation injury and leads to increased infection and mortality in mice: molecular mechanisms.
- The effects of ghrelin on inflammation and the immune system.
- Effect of combined radiation injury on cell death and inflammation in skin
- Novel therapeutic targets for sepsis: regulation of exaggerated inflammatory responses.
- Reduced plasma ghrelin levels on day 1 after esophagectomy: a new predictor of prolonged systemic inflammatory response syndrome
- Growth hormone releasing peptide-2, a ghrelin agonist, attenuates lipopolysaccharide-induced acute lung injury in rats.
- Inhibition of Intestinal Epithelial Apoptosis Improves Survival in a Murine Model of Radiation Combined Injury
- Ghrelin Suppresses Inflammation and Neuronal Nitric Oxide Synthase in Focal Cerebral Ischemia Via the Vagus Nerve
- Mechanism of the inhibitory effect of ghrelin in sepsis
- Relationship between gut and sepsis: Role of ghrelin.
- The Anti-Inflammatory and Neuroprotective Effects of Ghrelin in Subarachnoid Hemorrhage-Induced Oxidative Brain Damage in Rats
- Unraveling the link between leptin, ghrelin and different types of colitis
- Successful treatment of a case of extensive radiation burns with multiple organ dysfunction syndrome.
- Current trends in inflammatory and immunomodulatory mediators in sepsis
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