Crystal structure at 2.8 Å resolution of a soluble form of the cell adhesion molecule CD2
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Summary
The crystal structure of a soluble form of the T lymphocyte antigen CD2 provides the first complete view of the extracellular region of a cell adhesion molecule andCrystal contacts between these surfaces suggest a plausible model for the adhesive interaction.
- Type
- article
- Published
- 1992-11-19
- Cited by
- 293
- References
- 42
- OpenAlex
- https://openalex.org/W2037910920
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:4331192
Keywords
Linker, Molecule, Cell adhesion molecule, Adhesion, Cell adhesion
References
- Integrins: versatility, modulation, and signaling in cell adhesion.
- Molecular characteristics of recombinant human CD4 as deduced from polymorphic crystals.
- A role in transmembrane signaling for the cytoplasmic domain of the CD2 T lymphocyte surface antigen.
- Structure of antibody-antigen complexes: implications for immune recognition.
- Preliminary refinement and structural analysis of the Fab fragment from human immunoglobulin new at 2.0 A resolution.
- Structural and functional characterization of the CD2 immunoadhesion domain. Evidence for inclusion of CD2 in an alpha-beta protein folding class.
- Resolution of phase ambiguity in macromolecular crystallography.
- Preparation and analysis of protein crystals
- Domain association in immunoglobulin molecules. The packing of variable domains.
- The MRC OX‐45 antigen of rat leukocytes and endothelium is in a subset of the immunoglobulin superfamily with CD2, LFA‐3 and carcinoembryonic antigens.
- Micro-bridges for sitting-drop crystallizations
- Overlapping but nonidentical binding sites on CD2 for CD58 and a second ligand CD59.
- Crystallographic R Factor Refinement by Molecular Dynamics
- Monoclonal antibody and ligand binding sites of the T cell erythrocyte receptor (CD2)
- Crystal structure of a soluble form of the human T cell coreceptor CD8 at 2.6 A resolution.
- RIBBON: a stereo cartoon drawing program for proteins
- Cadherin cell adhesion receptors as a morphogenetic regulator.
- Molecular associations between the T-lymphocyte antigen receptor complex and the surface antigens CD2, CD4, or CD8 and CD5.
- The molecular structure of a dimer composed of the variable portions of the Bence-Jones protein REI refined at 2.0-A resolution.
- Methodology employed for the structure determination of tumour necrosis factor, a case of high non-crystallographic symmetry.
Cited by
- Finding the right fold
- Identification of the binding site in intercellular adhesion molecule 1 for its receptor, leukocyte function-associated antigen 1.
- The structural basis of human IgE–Fc receptor interactions
- Sequence specific 1H, 13C and15 N resonance assignment of rat CD2 domain 1
- A Review of REDCRAFT: Simultaneous Investigation of Structure and Dynamics of Proteins from RDC Restraints
- The structure of CD4.
- NMR exchange broadening arising from specific low affinity protein self-association: Analysis of nitrogen-15 nuclear relaxation for rat CD2 domain 1
- Substrate specificity of Glycine Oxidase and protein interaction specificity of the neuronal cell adhesion molecule TAG-1
- Molecular interactions at the T cell surface.
- Outils d'aide à l'étude des protéines: modélisation surfacique et visualisation sémantique des feuillets béta
- Strukturanalyse eines aminoterminalen Fragments des neuronalen Zelladhäsionsproteins Axonin-1 aus dem Huhn
- Using Protein Design to Understand the Role of Electrostatic Interactions on Calcium Binding Affinity and Molecular Recognition
- Determining The Site Specific Metal Binding and Structural Properties of EF-Hand Protein Using Grafting Approach
- Peptide-Mediated Inhibition of Neutrophil Transmigration by Blocking CD47 Interactions with Signal Regulatory Protein α1
- Overview of Protein Folds in the Immune System
- Expression cloning of an equine T-lymphocyte glycoprotein CD2 cDNA. Structure-based analysis of conserved sequence elements.
- Immunoglobulin superfamily cell adhesion molecules: zippers and signals.
- Protein Interactions between CD2 and Lck Are Required for the Lipid Raft Distribution of CD21
- Analysis of leukocyte membrane protein interactions using protein microarrays
- The immunoglobulin superfamily: Current Opinion in Structural Biology 1993, 3:846–852
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