Evidence for Multiple Sites of Interaction between IL‐12 and Its Receptor

Keywords

BETA (programming language), Protein subunit, Binding site, Chemistry, Molecular biology

References

• IL-12 receptor. I. Characterization of the receptor on phytohemagglutinin-activated human lymphoblasts.R Chizzonite, Theresa Truitt, Bhupesh B. Desai — 1992
• Human IL-12 p40 homodimer binds to the IL-12 receptor but does not mediate biologic activity.P Ling, Maurice K. Gately, Ueli Gubler — 1995
• Expression cloning of a human IL-12 receptor component. A new member of the cytokine receptor superfamily with strong homology to gp130.A O Chua, R Chizzonite, Bhupesh B. Desai — 1994
• Mouse interleukin‐12 (IL‐12) p40 homodimer: a potent IL‐12 antagonistSilke Gillessen, Daisy Carvajal, Ping Ling — 1995
• The interleukin‐12 subunit p40 specifically inhibits effects of the interleukin‐12 heterodimerFrank Mattner, Susanne Fischer, Stefanie Guckes — 1993

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• Dissection of CR1, factor H, membrane cofactor protein, and factor B binding and functional sites in the third complement component.John D. Lambris, Zisha Lao, T J Oglesby — 1996
• Novel IL-12 family members shed light on the orchestration of Th1 responsesFrank Brombacher — 2003
• Characterization of mouse interleukin‐12 p40 homodimer binding to the interleukin‐12 receptor subunitsXin Wang, Victoria L. Wilkinson, Frank Podlaski — 1999
• Interleukin-12 (IL-12)-driven alloimmune responses in vitro and in vivo: requirement for beta1 subunit of the IL-12 receptor.Joseph R. Piccotti, Kewang Li, Sherri Y. Chan — 1999
• Polymorphisms in the Il12b gene affect structure and expression of IL-12 in NOD and other autoimmune-prone mouse strainsSusie I. Ymer, D. Huang, Giuseppe Penna — 2002
• Liposomal Co-Entrapment of CD40mAb Induces Enhanced IgG Responses against Bacterial Polysaccharide and ProteinCaterina Hatzifoti, Andrew Bacon, Helen M. Marriott — 2008
• Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12.Birgit Oppmann, Robin Lesley, Bianca Blom — 2000
• A novel class of anti-IL-12p40 antibodiesAdam W. Clarke, Lynn D. Poulton, Hoi Yi Wai — 2010
• IL-23: A Cytokine That Acts on Memory T CellsDavid M. Frucht — 2002
• A Novel Role of CD30L/CD30 Signaling by T-T Cell Interaction in Th1 Response against Mycobacterial Infection1Ce Tang, Hisakata Yamada, Kensuke Shibata — 2008
• Alloantigen-reactive Th1 development in IL-12-deficient mice.Joseph R. Piccotti, Kewang Li, Sherri Y. Chan — 1998
• Cytokines during the pathogenesis of bronchiolitis obliterans syndromeJohn A. Belperio, Michael P. Keane, Robert M. Strieter — 2003
• Transcriptional regulation of the human interleukin-12 receptor beta2 geneJ. Rietschoten — 2002
• IL-23: A Cytokine That Acts on Memory T CellsDavid M. Frucht — 2002
• Potent neutralization via inhibition of IL-12-IL-12Rβ2 and IL-23-IL-23RAdam W. Clarke, L. Poulton, H. Wai — 2010
• Overview of Cytokine Structure and FunctionK. Csencsits, D. Bishop — 2004
• IL-12-Deficient Mice Alloantigen-Reactive Th 1 Development inJ. Piccotti, Kewang Li, Sherri Y. Chan — 1998
• CHAPTER 16 – Interleukin-12 Family [IL-12, 23, 12RA and 27]P. Kalinski, W. Storkus, A. Thomson — 2003
• This information is current as Mycobacterial Infection T-T Cell Interaction in Th 1 Response against A Novel Role of CD 30 L / CD 30 Signaling by YoshikaiCe Tang, H. Yamada, K. Shibata — 2008

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