Low body temperature in long-lived Ames dwarf mice at rest and during stress.
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Summary
The hypothesis that Ames dwarf mice, which live longer than normal size controls, maintain lower Tco than normals is supported, and their low Tco may be a result of reduced thermogenesis due to lack of those hormones.
- Type
- article
- Published
- 1999-09-01
- Cited by
- 106
- References
- 19
- OpenAlex
- https://openalex.org/W2031905630
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:23519725
Keywords
Homeothermy, Endocrinology, Cage, Hormone, Internal medicine
References
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- Effect of Chronic Caloric Restriction on the Circadian Regulation of Physiological and Behavioral Variables in Old Male B6C3F1 Mice
Cited by
- The effect of calorie restriction on insulin signaling in skeletal muscle and adipose tissue of Ames dwarf mice
- Congeneric variability in lifespan extension and onset of senescence suggest active regulation of aging in response to low temperature
- Energy Metabolism and Aging
- Linking oxidative stress and genetics of aging with p66Shc signaling and forkhead transcription factors
- Delayed aging in Ames dwarf mice. Relationships to endocrine function and body size.
- Life extension in the dwarf mouse.
- Effects of dietary restriction on the expression of insulin-signaling-related genes in long-lived mutant mice.
- Hypothesis: lifespan is regulated by chronomere DNA of the hypothalamus.
- The Shc locus regulates insulin signaling and adiposity in mammals
- Genetic pathways that regulate ageing in model organisms
- Reduced Levels of Thyroid Hormones, Insulin, and Glucose, and Lower Body Core Temperature in the Growth Hormone Receptor/Binding Protein Knockout Mouse
- Preweaning GH Treatment Normalizes Body Growth Trajectory and Reverses Metabolic Dysregulation in Adult Offspring After Maternal Undernutrition.
- Body composition of prolactin-, growth hormone-, and thyrotropin-deficient ames dwarf mice
- Could a deficiency in growth hormone signaling be beneficial to the aging brain?
- Hypothalamic and dietary control of temperature-mediated longevity
- The nature and mechanism of superoxide production by the electron transport chain: Its relevance to aging
- Being cool: how body temperature influences ageing and longevity
- Compromised respiratory adaptation and thermoregulation in aging and age-related diseases.
- Phospholipid composition and longevity: lessons from Ames dwarf mice
- IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice
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